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G2 DNA damage checkpoint

Known as: G2/M transition DNA damage checkpoint 
A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase in the cell cycle in response to DNA damage. [GOC… 
National Institutes of Health

Papers overview

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2013
2013
Dovitinib induces mitotic defects and activates the G2 DNA damage checkpoint
Dovitinib (TKI258; formerly CHIR‐258) is an orally bioavailable inhibitor of multiple receptor tyrosine kinases. Interestingly… 
Review
2013
Review
2013
Fission yeast nucleolar protein Dnt 1 regulates G 2 / M transition and cytokinesis through downregulating Wee 1 kinase
Cytokinesis involves temporally and spatially coordinated action of the cell cycle, cytoskeletal and membrane systems to achieve… 
2011
2011
Methods for studying the G2 DNA damage checkpoint in mammalian cells.
In response to post-replicative DNA damage, cells activate the G2 DNA damage checkpoint to ensure mitosis is not attempted until… 
2011
2011
First Report of Functional Chk1 siRNA Studies Applied to Drug Discovery
Commentary on: [Zehan Chen, Zhan Xiao, Jun Chen, Shi-Chung Ng, Thomas Sowin, Hing Sham, Saul Rosenberg, Steve Fesik, and… 
2007
2007
Inhibition of the G2 DNA damage checkpoint by oliveroline isolated from Duguetia odorata.
Plant extracts obtained from the U.S. National Cancer Institute's Open Repository collection have been screened for their ability… 
2006
2006
Antagonism of Chk1 Signaling in the G2 DNA Damage Checkpoint by Dominant Alleles of Cdr1
Activation of the Chk1 protein kinase by DNA damage enforces a checkpoint that maintains Cdc2 in its inactive, tyrosine-15 (Y15… 
Highly Cited
2002
Highly Cited
2002
The fission yeast pfh1(+) gene encodes an essential 5' to 3' DNA helicase required for the completion of S-phase.
The Cdc24 protein plays an essential role in chromosomal DNA replication in the fission yeast Schizosaccharomyces pombe, most… 
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