Fusion Proteins, gag-pol

Known as: gag pol Fused Protein, gag pol Fusion Proteins, gag-pol Protein 
Polyprotein products of a fused portion of retroviral mRNA containing the gag and pol genes. The polyprotein is synthesized only five percent of the… (More)
National Institutes of Health

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In BloodProcess of secretionagonistsantagonists & inhibitors
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Papers overview

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Highly Cited
2006
Highly Cited
2006
Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription.
We investigated the role of SIRT7, one of the seven members of the mammalian sirtuin family. We show that SIRT7 is a widely… (More)
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Highly Cited
2006
Highly Cited
2006
The transcriptional activity of RNA polymerase I is a key determinant for the level of all ribosome components.
Regulation of ribosome biogenesis is a key element of cell biology, not only because ribosomes are directly required for growth… (More)
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Highly Cited
2005
Highly Cited
2005
c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I
c-Myc coordinates cell growth and division through a transcriptional programme that involves both RNA polymerase (Pol) II- and… (More)
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Highly Cited
2004
Highly Cited
2004
mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability.
In cycling cells, transcription of ribosomal RNA genes by RNA polymerase I (Pol I) is tightly coordinated with cell growth. Here… (More)
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Highly Cited
2004
Highly Cited
2004
Nuclear actin and myosin I are required for RNA polymerase I transcription
The presence of actin and nuclear myosin I (NMI) in the nucleus suggests a role for these motor proteins in nuclear functions. We… (More)
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Highly Cited
2000
Highly Cited
2000
Localization of human immunodeficiency virus type 1 Gag and Env at the plasma membrane by confocal imaging.
Budding of lentiviruses occurs at the plasma membrane, but the preceding steps involved in particle assembly are poorly… (More)
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Highly Cited
1994
Highly Cited
1994
The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells.
The replication of human immunodeficiency virus type 1 (HIV-1) in nondividing host cells such as those of macrophage lineage is… (More)
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Highly Cited
1992
Highly Cited
1992
Ribosomal frameshifting efficiency and gag/gag-pol ratio are critical for yeast M1 double-stranded RNA virus propagation.
About 1.9% of ribosomes translating the gag open reading frame of the yeast L-A double-stranded RNA virus positive strand undergo… (More)
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Highly Cited
1990
Highly Cited
1990
An attempt to unify the structure of polymerases.
With the great availability of sequences from RNA- and DNA-dependent RNA and DNA polymerases, it has become possible to delineate… (More)
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Highly Cited
1988
Highly Cited
1988
Signals for ribosomal frameshifting in the Rous sarcoma virus gag-pol region.
The gag-pol protein of Rous sarcoma virus (RSV), the precursor to the enzymes responsible for reverse transcription and… (More)
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