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Freeze Fracturing

Known as: Fracturing, Freeze, Fracturings, Freeze, Freeze Fracturings 
Preparation for electron microscopy of minute replicas of exposed surfaces of the cell which have been ruptured in the frozen state. The specimen is… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1971-2017
010203019712017

Related topics

Related topics

3 relations
Freeze Etchingstandards characteristicsstatistics & numerical data

Related mentions per year

Related mentions per year

1946-2018
19401960198020002020
Freeze Fracturing
standards characteristics
Freeze Etching
statistics & numerical data

Papers overview

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Highly Cited
2007
Highly Cited
2007
Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease.
BACKGROUND Epithelial barrier function is impaired in Crohn's disease. AIM To define the underlying cellular mechanisms with… (More)
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2007
2007
Gap junctions on hippocampal mossy fiber axons demonstrated by thin-section electron microscopy and freeze fracture replica immunogold labeling.
Gap junctions have been postulated to exist between the axons of excitatory cortical neurons based on electrophysiological… (More)
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2007
2007
Freeze-fracture electron microscopy
The freeze-fracture technique consists of physically breaking apart (fracturing) a frozen biological sample; structural detail… (More)
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2002
2002
Identification of cellular sections with imaging mass spectrometry following freeze fracture.
Freeze-fracture techniques have been used to maintain chemical heterogeneity of frozen-hydrated mammalian cells for static TOF… (More)
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1999
1999
Freeze-fracture and cytochemical evidence for structural and functional alteration in the axolemma and myelin sheath of adult guinea pig optic nerve fibers after stretch injury.
Recent work in animal models of human diffuse axonal injury has generated the hypothesis that, rather than there being physical… (More)
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Highly Cited
1997
Highly Cited
1997
Grid-mapped freeze-fracture analysis of gap junctions in gray and white matter of adult rat central nervous system, with evidence for a "panglial syncytium" that is not coupled to neurons.
In white matter regions of the brain and spinal cord of adult mammals, gap junctions previously were observed linking astrocytes… (More)
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Highly Cited
1996
Highly Cited
1996
Occludin is a functional component of the tight junction.
Occludin's role in mammalian tight junction activity was examined by 'labeling' the occludin pool with immunologically detectable… (More)
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Highly Cited
1985
Highly Cited
1985
Membrane stabilization during freezing: the role of two natural cryoprotectants, trehalose and proline.
The relative effectiveness of two natural cryoprotectants, proline and trehalose, in preserving membrane structure and function… (More)
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1979
1979
Distribution of transmembrane polypeptides in freeze fracture.
Human erythrocytes have been freeze-fractured, and the polypeptides associated with the separate halves of the membrane bilayer… (More)
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1977
1977
[Freeze fracture study of Toxoplasma and Sarcocystis infective stages (author's transl)].
Infective stages of Toxoplasma and Sarcocystis have been studied by the freeze fracture technique. The outer membrane of the… (More)
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