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Fluorescein-5-isothiocyanate

Known as: Fluorescein 5 isothiocyanate, Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 3',6'-dihydroxy-5-isothiocyanato-, fluorescein-5-isothiocyanate (FITC) 
Fluorescent probe capable of being conjugated to tissue and proteins. It is used as a label in fluorescent antibody staining procedures as well as… 
National Institutes of Health

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18 relations

Narrower (13)

4-amino-N-fluorescein isothiocyanate-17-estradiolFITC-tyramideN-(fluorescein-thioureanyl)glutamateestradiol 6-O-carboxymethyloxime-bovine serum albumin-fluorescein isothiocyanate

Broader (1)

Fluorescent Dyes
analogs & derivativesaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Design and synthesis of pH-responsive polymeric carriers that target uptake and enhance the intracellular delivery of oligonucleotides.
Highly Cited
1998
Highly Cited
1998
Monocytes from Wiskott-Aldrich patients display reduced chemotaxis and lack of cell polarization in response to monocyte chemoattractant protein-1 and formyl-methionyl-leucyl-phenylalanine.
Wiskott-Aldrich syndrome (WAS) is an X-linked disorder characterized by trombocytopenia, eczema, and progressive decline of the… 
Highly Cited
1998
Highly Cited
1998
A Dominant-negative Clathrin Mutant Differentially Affects Trafficking of Molecules with Distinct Sorting Motifs in the Class II Major Histocompatibility Complex (MHC) Pathway
The role of clathrin in intracellular sorting was investigated by expression of a dominant-negative mutant form of clathrin… 
Highly Cited
1991
Highly Cited
1991
Modulation of mouse complement receptors 1 and 2 suppresses antibody responses in vivo.
A mAb, 7G6, that binds to mouse CR1 and CR2 and down-modulates their expression on splenic B cells in vivo, was used to determine… 
Highly Cited
1990
Highly Cited
1990
Membrane electroporation--fast molecular exchange by electroosmosis.
Highly Cited
1990
Highly Cited
1990
Rapid subchromosomal localization of cosmids by nonradioactive in situ hybridization.
A rapid method for localizing large numbers of complete cosmids by nonradioactive in situ hybridization is described. The cosmids… 
Highly Cited
1990
Highly Cited
1990
Generation and characterization of Dictyostelium cells deficient in a myosin I heavy chain isoform
Motile activities such as chemotaxis and phagocytosis, which occur in Dictyostelium cells lacking myosin II, may be dependent… 
Highly Cited
1987
Highly Cited
1987
Use of whole blood methods in assessment of immune parameters in immunodeficiency states.
Whole blood (WB) methods requiring less than 4 ml heparinized peripheral blood were used to define mononuclear cell phenotype… 
Highly Cited
1977
Highly Cited
1977
Role of lectins in plant-microorganism interactions: I. Binding of soybean lectin to rhizobia.
Highly purified soybean lectin (SBL) was labeled with fluorescein isothiocyanate (FITC-SBL) or tritium ((3)H-SBL) and repurified… 
Highly Cited
1973
Highly Cited
1973
Conjugates of Immunoglobulin G with Different Fluorochromes. I. Characterization by Anionic‐exchange Chromatography
The conjugation of purified IgG for 1 hour at room temperature and pH 9.5 was found to be a simple and reproducible method useful… 
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