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Filipin

Known as: Filipin [Chemical/Ingredient], Desoxylagosin, Filimarisin 
A complex of polyene antibiotics obtained from Streptomyces filipinensis. Filipin III alters membrane function by interfering with membrane sterols… 
National Institutes of Health

Related topics

Related topics

12 relations

Narrower (1)

32,33-didehydroroflamycoin

Broader (4)

Anti-Bacterial AgentsAntifungal AgentsAntiviral AgentsPolyenes
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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2006
2006
Endocytosis pathways in endothelium: how many?
  • R. Stan
  • American Journal of Physiology - Lung cellular…
  • 2006
  • Corpus ID: 33865180
vascular endothelium is a cellular monolayer with the organization of a simple squamous epithelium that lines the entire… 
1995
1995
Changes in free cholesterol content, measured by filipin fluorescence and flow cytometry, correlate with changes in cholesterol biosynthesis in THP-1 macrophages.
The free cholesterol content of cells can be monitored by the intensity of fluorescence emissions from the polyene antibiotic… 
Highly Cited
1984
Highly Cited
1984
Filipin-positive, oil red O-negative particles in atherosclerotic lesions induced by cholesterol feeding.
  • H. Kruth
  • Laboratory investigation; a journal of technical…
  • 1984
  • Corpus ID: 32603568
In this study, extracellular spherical filipin-positive particles have been demonstrated using the fluorescent cholesterol probe… 
1981
1981
Characterization of isolated rat-liver cells made permeable with filipin.
When isolated rat-liver cells were incubated for 1 min at 37 degrees C with filipin at a concentration of 50 microM, the plasma… 
1981
1981
Determination of cholesterol asymmetry by rapid kinetics of filipin-cholesterol association: effect of modification in lipids and proteins.
The rapid kinetic behavior of filipin association with cholesterol was unaffected by binding of water-soluble proteins to vesicle… 
1980
1980
Opposite polarity of filipin-induced deformations in the membrane of condensing vacuoles and zymogen granules.
Filipin binding to membrane sterols induces deformations of the membrane that are detected by freeze-fracture either as 20- to 25… 
1978
1978
Effects of the antidiuretic hormone, arginine vasotocin, theophylline, filipin and A23187 on cyclic AMP in isolated frog skin epithelium (Rana temporaria).
A method for measuring cAMP in frog skin epithelium was developed. The epithelia were isolated after collagenase-treatment. cAMP… 
Highly Cited
1965
Highly Cited
1965
Effect of Cholesterol on the Sensitivity of Mycoplasma laidlawii to the Polyene Antibiotic Filipin
Weber, Morton M. (St. Louis University School of Medicine, St. Louis, Mo.), and Stephen C. Kinsky. Effect of cholesterol on the… 
Highly Cited
1964
Highly Cited
1964
ACTION OF THE POLYENE ANTIBIOTICS FILIPIN, NYSTATIN AND N-ACETYLCANDIDIN ON THE YEAST CELL MEMBRANE.
Summary: The effects of the antifungal polyene antibiotics n-acetylcandidin, nystatin and filipin on the yeast cell membranes… 
Highly Cited
1961
Highly Cited
1961
ALTERATIONS IN THE PERMEABILITY OF NEUROSPORA CRASSA DUE TO POLYENE ANTIBIOTICS
Kinsky, Stephen C. (Washington University, St. Louis, Mo.). Alterations in the permeability of Neurospora crassa due to polyene… 
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