Filipin

Known as: Filipin [Chemical/Ingredient], Desoxylagosin, Filimarisin 
A complex of polyene antibiotics obtained from Streptomyces filipinensis. Filipin III alters membrane function by interfering with membrane sterols… (More)
National Institutes of Health

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Highly Cited
2005
Highly Cited
2005
We investigated the effects of inhibitors of clathrin-mediated endocytosis (chlorpromazine and K(+) depletion) and of caveolae… (More)
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Highly Cited
2002
Highly Cited
2002
Conversion of the normal membrane-bound prion protein (PrP-sen) to its pathological isoform (PrP-res) is a key event in the… (More)
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Highly Cited
2001
Highly Cited
2001
PURPOSE To determine the cholesterol composition of normal human Bruch's membrane and choroid as a function of age and retinal… (More)
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2001
2001
Methyl-beta-cyclodextrin and filipin are cholesterol-binding reagents often used interchangeably to investigate functional… (More)
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Highly Cited
2001
Highly Cited
2001
The mechanism of cholera toxin (CT) internalization has been investigated using Caco-2 cells transfected with caveolin to induce… (More)
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Highly Cited
1998
Highly Cited
1998
The mechanism by which cholera toxin (CT) is internalized from the plasma membrane before its intracellular reduction and… (More)
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Highly Cited
1998
Highly Cited
1998
Cholesterol is an important constituent of most mammalian cell membranes and its concentration in various cellular membranes is… (More)
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Highly Cited
1994
Highly Cited
1994
Caveolae or noncoated plasmalemmal vesicles found in a variety of cells have been implicated in a number of important cellular… (More)
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1984
1984
Filipin, a mixture of polyene antibiotics which form complexes with cholesterol, perturbs membrane lipid organization, and causes… (More)
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Highly Cited
1981
Highly Cited
1981
The Golgi apparatus is a key element in the ordered movement of secretory polypeptides from the rough endoplasmic reticulum to… (More)
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