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Fibrillins

Known as: Fibrillin, Fibrillins [Chemical/Ingredient] 
A family of extracellular matrix glycoproteins that is structurally similar to LATENT TGF-BETA BINDING PROTEINS, but contain additional TGF-beta… 
National Institutes of Health

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FBN1 geneIn BloodProcess of secretionagonists

Papers overview

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2005
2005
Development of a new in vitro model of elastic fiber assembly in human pigmented epithelial cells.
Highly Cited
2003
Highly Cited
2003
Fibrillin-1 and -2 contain heparin-binding sites important for matrix deposition and that support cell attachment.
Fibrillin-1 and -2 are large modular extracellular matrix glycoproteins found in many vertebrate organ systems and are known to… 
Highly Cited
2000
Highly Cited
2000
The microfibrillar proteins MAGP-1 and fibrillin-1 form a ternary complex with the chondroitin sulfate proteoglycan decorin.
MAGP-1 and fibrillin-1, two protein components of extracellular microfibrils, were shown by immunoprecipitation studies to… 
Highly Cited
1999
Highly Cited
1999
The Integrin avb6 Binds and Activates Latent TGFb1: A Mechanism for Regulating Pulmonary Inflammation and Fibrosis
Summary The mechanisms involved in activating latent TGFb are not fully understood, but recently there has been Transforming… 
Highly Cited
1999
Highly Cited
1999
N-terminal domains of fibrillin 1 and fibrillin 2 direct the formation of homodimers: a possible first step in microfibril assembly.
Aggregation of fibrillin molecules via disulphide bonds is postulated to be an early step in microfibril assembly. By expressing… 
Highly Cited
1999
Highly Cited
1999
Collagen XVI is expressed by human dermal fibroblasts and keratinocytes and is associated with the microfibrillar apparatus in the upper papillary dermis.
Highly Cited
1998
Highly Cited
1998
Microfibril-associated Glycoprotein-2 (MAGP-2) Is Specifically Associated with Fibrillin-containing Microfibrils but Exhibits More Restricted Patterns of Tissue Localization and Developmental…
SUMMARY We developed an affinity-purified anti-MAGP-2 peptide antibody that specifically identified MAGP-2 on Western blots of… 
Highly Cited
1996
Highly Cited
1996
Functional domains on elastin and microfibril-associated glycoprotein involved in elastic fibre assembly.
Studies in vitro suggest that the C-terminus of tropoelastin mediates elastin polymerization through an interaction with… 
Highly Cited
1995
Highly Cited
1995
An extracellular matrix protein of jellyfish homologous to mammalian fibrillins forms different fibrils depending on the life stage of the animal.
A monoclonal antibody generated against the isolated extracellular matrix (ECM) of the medusa Podocoryne carnea M. Sars… 
Highly Cited
1990
Highly Cited
1990
Fibrillin immunoreactive fibers constitute a unique network in the human dermis: immunohistochemical comparison of the distributions of fibrillin, vitronectin, amyloid P component, and orcein…
Fibrillin, a 350-kD glycoprotein, was recently localized to elastin-associated 10 nm microfibrils. Here, the distribution of… 
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