FBN1 gene

Known as: OCTD, Fibrillin 1 Gene, FIBRILLIN 1 
This gene is involved in the maintenance of connective tissue.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Dynamic, mRNA-containing stress granules (SGs) form in the cytoplasm of cells under environmental stresses, including viral… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND TGFBR2 mutations were recognized recently among patients with a Marfan-like phenotype. The associated clinical and… (More)
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2003
2003
Fibrillins are the major glycoprotein components of microfibrils that form a template for tropoelastin during elastic… (More)
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Highly Cited
2002
Highly Cited
2002
The angiopoietin family of secreted factors is functionally defined by the C-terminal fibrinogen (FBN)-like domain, which… (More)
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2001
2001
Mutations in the fibrillin -1 gene (FBN1) cause Marfan syndrome (MFS), an autosomal dominant multi-system connective tissue… (More)
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Highly Cited
1999
Highly Cited
1999
Fibrillin is the principal structural component of the 10-12 nm diameter elastic microfibrils of the extracellular matrix. We… (More)
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Highly Cited
1996
Highly Cited
1996
Mice carrying the Tight skin (Tsk) mutation have thickened skin and visceral fibrosis resulting from an accumulation of… (More)
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Highly Cited
1991
Highly Cited
1991
MARFAN syndrome is an inherited disorder of connective tissue manifested in the ocular, skeletal and cardiovascular systems. It… (More)
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Highly Cited
1991
Highly Cited
1991
FIBRILLIN is a large (relative molecular mass 350,000) glyco-protein which can be isolated from fibroblast cell cultures and is a… (More)
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Highly Cited
1986
Highly Cited
1986
A new connective tissue protein, which we call fibrillin, has been isolated from the medium of human fibroblast cell cultures… (More)
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