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Fertilins

Known as: PH 30 Fusion Protein, Fertilin Protein, PH 30 Protein 
Sperm surface proteins involved in sperm-egg fusion. They consist of two subunits, fertilin alpha (ADAM1a) and beta (ADAM2), both of which belong to… 
National Institutes of Health

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Fertilin betafertilin alpha
In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects

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Highly Cited
2001
Highly Cited
2001
Testase 1 (ADAM 24) a plasma membrane-anchored sperm protease implicated in sperm function during epididymal maturation or fertilization.
Plasma membrane-anchored proteases have key roles in cell signaling, migration and refashioning the cell surface and its… 
Highly Cited
2000
Highly Cited
2000
Identification of Key Functional Amino Acids of the Mouse Fertilin β (ADAM2) Disintegrin Loop for Cell-Cell Adhesion during Fertilization*
Fertilin β (also known as ADAM2) is a cell adhesion molecule on the surface of mammalian sperm that participates in sperm-egg… 
Highly Cited
1999
Highly Cited
1999
Interaction of metargidin (ADAM-15) with αvβ3 and α5β1 integrins on different haemopoietic cells
Metargidin (ADAM-15) is a type I transmembrane glycoprotein belonging to the ADAM (A Disintegrin and Metalloprotease Domain… 
Highly Cited
1998
Highly Cited
1998
Sequence analysis of a variety of primate fertilin α genes: Evidence for non‐functional genes in the gorilla and man
The sperm surface fertilin complex was first described in the guinea pig where it was found as a heterodimer of α and β subunits… 
Highly Cited
1997
Highly Cited
1997
The human fertilin alpha gene is non-functional: implications for its proposed role in fertilization.
In the guinea-pig, the alpha subunit of the fertilin complex, a heterodimeric surface membrane glycoprotein found on the head… 
Highly Cited
1997
Highly Cited
1997
Characterization of the binding of recombinant mouse sperm fertilin alpha subunit to mouse eggs: evidence for function as a cell adhesion molecule in sperm-egg binding.
Fertilin (previously known as PH-30) is a sperm protein that is a candidate molecule for mediating the binding and fusion of the… 
1997
1997
Cloning and sequence analysis of rat fertilin alpha and beta--developmental expression, processing and immunolocalization.
Fertilin alpha and beta are members of the MDC (metalloproteinase-like, disintegrin-like, cysteine-rich) protein family and are… 
1996
1996
Molecular cloning of the human fertilin beta subunit.
Fertilin, a heterodimeric sperm surface protein, first identified in guinea pig, has been shown to play an important role in… 
1996
1996
Cloning and expression of recombinant rabbit fertilin
Fertilin is a sperm surface protein complex which is reported to play an essential role in sperm‐egg fusion in mammals. It is… 
Highly Cited
1995
Highly Cited
1995
Mouse sperm-egg plasma membrane interactions: analysis of roles of egg integrins and the mouse sperm homologue of PH-30 (fertilin) beta.
The guinea pig sperm protein, PH-30 (also known as fertilin), is postulated to participate in the interaction between the sperm… 
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