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Ferriprotoporphyrin IX

National Institutes of Health

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Hemin

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Highly Cited
2009
Highly Cited
2009
Speciation of ferriprotoporphyrin IX in aqueous and mixed aqueous solution is controlled by solvent identity, pH, and salt concentration.
The speciation of ferriprotoporphyrin IX (Fe(III)PPIX) in aqueous and mixed aqueous-organic solvents has been investigated by UV… 
2003
2003
Potentiation of the antimalarial action of chloroquine in rodent malaria by drugs known to reduce cellular glutathione levels.
2003
2003
The treatment of Plasmodium falciparum-infected erythrocytes with chloroquine leads to accumulation of ferriprotoporphyrin IX bound to particular parasite proteins and to the inhibition of the…
Ferriprotoporphyrin IX (FPIX) is a potentially toxic product of hemoglobin digestion by intra-erythrocytic malaria parasites. It… 
Highly Cited
2001
Highly Cited
2001
Histidine-rich protein 2 of the malaria parasite, Plasmodium falciparum, is involved in detoxification of the by-products of haemoglobin degradation.
Highly Cited
1999
Highly Cited
1999
Cellular Uptake of Chloroquine Is Dependent on Binding to Ferriprotoporphyrin IX and Is Independent of NHE Activity in Plasmodium falciparum
Here we provide definitive evidence that chloroquine (CQ) uptake in Plasmodium falciparum is determined by binding to… 
Highly Cited
1992
Highly Cited
1992
Heme polymerase: modulation by chloroquine treatment of a rodent malaria.
Highly Cited
1987
Highly Cited
1987
The state of ferriprotoporphyrin IX in malaria pigment.
Highly Cited
1982
Highly Cited
1982
Lysis of Plasmodium falciparum by ferriprotoporphyrin IX and a chloroquine-ferriprotoporphyrin IX complex
Ferriprotoporphyrin IX (FP) and a chloroquine-FP complex lysed isolated Plasmodium falciparum parasites as judged by decreases in… 
Highly Cited
1981
Highly Cited
1981
Mechanism of hemolysis induced by ferriprotoporphyrin IX.
Incubation of a 0.5% suspension of washed, normal mouse erythrocytes with ferriprotoporphyrin IX (FP) at 37 degrees C and pH 7.4… 
Highly Cited
1980
Highly Cited
1980
Hemolysis of mouse erythrocytes by ferriprotoporphyrin IX and chloroquine. Chemotherapeutic implications.
Incubation of a 0.5% suspension of washed normal mouse erythrocytes with ferriprotoporphyrin IX (FP) for 2.5 h at 37 degrees C… 
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