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Fendiline
Known as:
Benzenepropanamine, gamma-phenyl-N-(1-phenylethyl)-
, Fendilin
, Fendiline [Chemical/Ingredient]
Coronary vasodilator; inhibits calcium function in muscle cells in excitation-contraction coupling; proposed as antiarrhythmic and antianginal agents…
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National Institutes of Health
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Related topics
Related topics
11 relations
Broader (1)
Calcium Channel Blockers
In Blood
agonists
analogs & derivatives
antagonists & inhibitors
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Narrower (3)
KHL 8430
Sensit
fendiline hydrochloride
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Inhibition of Acid Sphingomyelinase Depletes Cellular Phosphatidylserine and Mislocalizes K-Ras from the Plasma Membrane
Kwang-jin Cho
,
Dharini van der Hoeven
,
+5 authors
J. Hancock
Molecular and Cellular Biology
2015
Corpus ID: 3847660
ABSTRACT K-Ras must localize to the plasma membrane for biological activity; thus, preventing plasma membrane interaction blocks…
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2015
2015
Fendiline inhibits proliferation and invasion of pancreatic cancer cells by interfering with ADAM10 activation and β-catenin signaling
N. Woods
,
J. Trevino
,
D. Coppola
,
S. Chellappan
,
Shengyu Yang
,
J. Padmanabhan
OncoTarget
2015
Corpus ID: 9673051
ADAM10 (A Disintegrin and Metalloprotease Domain 10) affects the pathophysiology of various cancers, and we had shown that…
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2002
2002
Arylalkylamines are a novel class of positive allosteric modulators at GABA(B) receptors in rat neocortex.
D. Kerr
,
J. Ong
,
N. M. Puspawati
,
R. Prager
European Journal of Pharmacology
2002
Corpus ID: 38814875
1998
1998
Open state block by fendiline of L-type Ca++ channels in ventricular myocytes from rat heart.
H. Nawrath
,
G. Klein
,
J. Rupp
,
J. Wegener
,
A. Shainberg,
Journal of Pharmacology and Experimental…
1998
Corpus ID: 15439873
The effects of fendiline on L-type Ca++ currents [ICa(L)] were investigated in rat ventricular cardiomyocytes using the patch…
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1988
1988
The influence of calcium channel blockers on superoxide anions.
F. Shridi
,
J. Robak
Pharmacological Research Communications
1988
Corpus ID: 27971809
Highly Cited
1987
Highly Cited
1987
Differential effects of calcium entry blockers on pre- and postsynaptic influx of calcium in the rat hippocampus in vitro
Roland S. G. Jones
,
U. Heinemann
Brain Research
1987
Corpus ID: 26920440
Review
1987
Review
1987
Fendiline: a review of its basic pharmacological and clinical properties.
R. Bayer
,
R. Mannhold
Pharmatherapeutica
1987
Corpus ID: 26952058
Fendiline is an anti-anginal agent for the treatment of coronary heart disease. Together with other diphenylalkylamines it is sub…
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1987
1987
Calmodulin antagonism: a pharmacological approach for the inhibition of mediator release from mast cells.
G. Gigl
,
D. Hartweg
,
E. Sánchez-Delgado
,
G. Metz
,
K. Gietzen
Cell Calcium
1987
Corpus ID: 4284774
Highly Cited
1983
Highly Cited
1983
Interaction of verapamil and other calcium channel blockers with alpha 1- and alpha 2-adrenergic receptors.
H. Motulsky
,
M. Snavely
,
R. J. Hughes
,
P. Insel
Circulation Research
1983
Corpus ID: 33495087
To determine the specificity of the previously demonstrated competition of verapamil with radioligand binding to alpha-adrenergic…
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Highly Cited
1983
Highly Cited
1983
A fluorescent calmodulin that reports the binding of hydrophobic inhibitory ligands.
J. Johnson
,
L. Wittenauer
Biochemical Journal
1983
Corpus ID: 19778212
Ca2+ binding to calmodulin in the pCa range 5.5-7.0 exposes hydrophobic sites that bind hydrophobic inhibitory ligands, including…
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