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Fendiline

Known as: Benzenepropanamine, gamma-phenyl-N-(1-phenylethyl)-, Fendilin, Fendiline [Chemical/Ingredient] 
Coronary vasodilator; inhibits calcium function in muscle cells in excitation-contraction coupling; proposed as antiarrhythmic and antianginal agents… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
ABSTRACT Ras proteins regulate signaling pathways important for cell growth, differentiation, and survival. Oncogenic mutant Ras… Expand
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Highly Cited
2004
Highly Cited
2004
Summary1.The proposal that calcium antagonists have different sites of action has been tested by attempting to reverse their… Expand
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1998
1998
The effects of fendiline on L-type Ca++ currents [ICa(L)] were investigated in rat ventricular cardiomyocytes using the patch… Expand
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Highly Cited
1992
Highly Cited
1992
The possibility that calmodulin inhibitors impair the constitutive but not the inducible nitric oxide synthase(s)-mediated… Expand
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Highly Cited
1990
Highly Cited
1990
Stimulation of soluble guanylyl cyclase in rat fetal lung fibroblasts (RFL-6 cells) was used as a sensitive assay for endothelium… Expand
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Highly Cited
1987
Highly Cited
1987
A decrease in extracellular free Ca ([Ca2+]o) in response to stimulation of Schaffer collaterals could be recorded in or near the… Expand
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Review
1983
Review
1983
The discovery of Ca++ antagonism as a new principle of action of coronary drugs reaches back to 1964, when we reported that two… Expand
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Highly Cited
1983
Highly Cited
1983
Ca2+ binding to calmodulin in the pCa range 5.5-7.0 exposes hydrophobic sites that bind hydrophobic inhibitory ligands, including… Expand
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Highly Cited
1983
Highly Cited
1983
To determine the specificity of the previously demonstrated competition of verapamil with radioligand binding to alpha-adrenergic… Expand
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Highly Cited
1982
Highly Cited
1982
The effect of Ca2+ antagonist drugs on Ca2+ uptake and Na+-induced Ca2+ release by isolated rabbit heart mitochondria has been… Expand
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