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Advanced age is the main risk factor for most chronic diseases and functional deficits in humans, but the fundamental mechanisms… Expand In a healthy body, ROS (reactive oxygen species) and antioxidants remain in balance. When the balance is disrupted towards an… Expand There is accumulating evidence that workplace exposure to toxic substances contributes to male infertility. Men suffering from… Expand The peroxisome proliferator-activated receptors (PPARs) are a group of three nuclear receptor isoforms, PPAR gamma, PPAR alpha… Expand The adipocyte-specific hormone leptin, the product of the obese (ob) gene,regulates adipose-tissue mass through hypothalamic… Expand A new gene, termed klotho, has been identified that is involved in the suppression of several ageing phenotypes. A defect in… Expand The signals regulating ovarian follicle development and the mechanisms by which they are communicated are largely undefined1. At… Expand ObjectiveThis report documents that the gastric bypass operation provides long-term control for obesity and diabetes. Summary… Expand OBJECTIVE--To investigate whether semen quality has changed during the past 50 years. DESIGN--Review of publications on semen… Expand Clinical gynecologic endocrinology and infertility , Clinical gynecologic endocrinology and infertility… Expand