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Fed-Batch Culture Techniques

Known as: Fed-Batch Culture, Culture Technique, Fed-Batch, Cultures, Continuous Batch 
Batch cell culture technique where the culture is fed with nutrients throughout the process, instead of all at once in the beginning.
National Institutes of Health

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Batch Cell Culture Techniques

Papers overview

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Highly Cited
2001
Highly Cited
2001
Production of a novel bioflocculant by fed-batch culture of Citrobacter sp.
Production of a novel bioflocculant by a fed-batch culture of Citrobacter sp. TKF04 was investigated using acetic acid as a sole… 
Highly Cited
1998
Highly Cited
1998
Optimising fed-batch production of recombinant proteins using the baculovirus expression vector system.
Fed-batch culture can offer significant improvement in recombinant protein production compared to batch culture in the… 
1998
1998
Improvement of Heterologous Protein Productivity by Controlling Postinduction Specific Growth Rate in Recombinant Escherichia coli under Control of the PL Promoter
To develop the optimal operational strategy for the PL promoter of interferon (IFN)‐γ‐producing Escherichia coli, some rational… 
Highly Cited
1997
Highly Cited
1997
Elucidation of the mechanism of lactic acid growth inhibition and production in batch cultures of Lactobacillus rhamnosus
Abstract Batch cultures of Lactobacillus rhamnosus were carried out at different pH values in order to study the limitation of… 
Highly Cited
1997
Highly Cited
1997
Alcohol fermentation of starch by a genetic recombinant yeast having glucoamylase activity.
Alcohol fermentation of starch was investigated using a direct starch fermenting yeast, Saccharomyces cerevisiae SR93… 
Review
1997
Review
1997
Integrated approaches to the design of media and feeding strategies for fed-batch cultures of animal cells.
Highly Cited
1996
Highly Cited
1996
Enhancement of survivability of mammalian cells by overexpression of the apoptosis-suppressor gene bcl-2.
Cell lines derived from the hemopoetic lineages are widely used as hosts for the production of biologicals. These cell lines have… 
Highly Cited
1995
Highly Cited
1995
Lactose fed-batch overexpression of recombinant metalloproteins in Escherichia coli BL21 (DE3): process control yielding high levels of metal-incorporated, soluble protein.
A method for producing recombinant proteins in pilot scale fermentation equipment using a glucose fed-batch initial growth… 
1990
1990
Shear Sensitivity of Hybridoma Cells in Batch, Fed‐Batch, and Continuous Cultures
Previously, we observed that CRL‐8018 hybridoma cells were more sensitive to well‐defined viscometric shear during the lag and… 
1988
1988
Application of fed‐batch culture to citric acid production by Aspergillus niger: The effects of dilution rate and dissolved oxygen tension
Studies in conventional batch culture confirmed that the maximum citric acid production rate occurred prior to exhaustion of the… 
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