Fatty Acid Desaturase 1

Known as: EC1.14.19.-, Delta(5) Desaturase, Delta(5) Fatty Acid Desaturase 
Fatty acid desaturase 1 (444 aa, ~52 kDa) is encoded by the human FADS1 gene. This protein plays a role in catalyzing saturation and desaturation of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2017
02419852017

Papers overview

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2015
2015
BACKGROUND An association between desaturase activity and risk of type 2 diabetes (T2D) has been found in epidemiologic studies… (More)
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2013
2013
Δ9-Desaturase (stearoyl-CoA desaturase 1, SCD-1) regulates the desaturation of SFA, mainly stearic and palmitic, to MUFA. Δ6… (More)
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2013
2013
BACKGROUND AND AIM We examined the association of fatty acid (FA) composition in serum phospholipids with the features of… (More)
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2012
2012
Compared with diets high in fat, low-fat diets are associated with reduced risk of cardiovascular disease. We hypothesized that a… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND The long-term role of fatty acids (FAs) in the cause of diabetes remains largely unclear. OBJECTIVE We aimed to… (More)
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Highly Cited
2007
Highly Cited
2007
Fatty acid desaturases introduce double bonds into growing fatty acid chains. The key desaturases in humans are Δ5-desaturase… (More)
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2007
2007
On the molecular level, essential fatty acid deficiency (EFAD) has been associated with induced fatty acid (FA) desaturase… (More)
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2006
2006
The purpose of this work was to study whether rat lactating mammary gland can synthesize PUFAs through the expression of D5 and… (More)
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Highly Cited
2005
Highly Cited
2005
Types of dietary fat have been related to components of the metabolic syndrome. Serum fatty acid composition mainly reflects… (More)
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Highly Cited
2002
Highly Cited
2002
In the process of seeking sterol regulatory element-binding protein 1a (SREBP-1a) target genes, we identified and cloned a cDNA… (More)
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