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Obesity and type 2 diabetes are characterized by altered gut microbiota, inflammation, and gut barrier disruption. Microbial… Expand Advanced age is the main risk factor for most chronic diseases and functional deficits in humans, but the fundamental mechanisms… Expand Overweight and obesity affects more than 66% of the adult population and is associated with a variety of chronic diseases. Weight… Expand Non-thrombotic PE does not represent a distinct clinical syndrome. It may be due to a variety of embolic materials and result in… Expand Editor's Note: This issue of In the Clinic has been updated. More than 30% of U.S. adults are obese (1). Generally defined as a… Expand Background— Visceral adipose tissue (VAT) compartments may confer increased metabolic risk. The incremental utility of measuring… Expand It now appears that, in most obese patients, obesity is associated with a low-grade inflammation of white adipose tissue (WAT… Expand Insulin resistance is a major factor in the pathogenesis of type 2 diabetes in the elderly. To investigate how insulin resistance… Expand The prevalence of obesity among children is high and is increasing. We know that obesity runs in families, with children of obese… Expand In a prospective study of risk factors for ischaemic heart disease 792 54 year old men selected by year of birth (1913) and… Expand