FAQ

Fanconi Anemia Group B Protein

Known as: FAAP95, Protein FACB, FANCB 
Fanconi anemia group B protein (859 aa, ~98 kDa) is encoded by the human FANCB gene. This protein may play a role in both ubiquitination and DNA… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2017
0120042017

Related topics

Related topics

10 relations
BARD1 PathwayBRCA2 ProteinBRCA2 wt AlleleCell Cycle Control
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Related mentions per year

Related mentions per year

1949-2018
19401960198020002020
Fanconi Anemia Group B Protein
DNA Repair
Cell Cycle Control
Ubiquitination
Fanconi Anemia
BRCA2 wt Allele

Papers overview

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2018
2018
Mutational and Functional Analysis of FANCB as a Candidate Gene for Sporadic Head and Neck Squamous Cell Carcinomas.
BACKGROUND/AIM Head and neck squamous cell carcinomas (HNSCCs) form a heterogeneous tumor entity located throughout the oral… (More)
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2017
2017
X-linked VACTERL-H caused by deletion of exon 3 in FANCB: A case report.
 
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2015
2015
Fancb deficiency impairs hematopoietic stem cell function
Fanconi anemia (FA) is a genetic disorder characterized by bone marrow failure, variable congenital malformations and a… (More)
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2010
2010
Inactivation of the tumor suppressor genes causing the hereditary syndromes predisposing to head and neck cancer via promoter hypermethylation in sporadic head and neck cancers.
Fanconi anemia (FA) and dyskeratosis congenita (DC) are rare inherited syndromes that cause head and neck squamous cell cancer… (More)
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Highly Cited
2008
Highly Cited
2008
Analysis of FANCB and FANCN/PALB2 Fanconi Anemia genes in BRCA1/2-negative Spanish breast cancer families
Recent reports have shown that mutations in the FANCJ/BRIP1 and FANCN/PALB2 Fanconi Anemia (FA) genes confer a moderate breast… (More)
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Review
2005
Review
2005
New advances in the DNA damage response network of Fanconi anemia and BRCA proteins. FAAP95 replaces BRCA2 as the true FANCB protein.
Fanconi anemia (FA) proteins function in a DNA damage response pathway that appears to be part of the network including breast… (More)
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Highly Cited
2004
Highly Cited
2004
X-linked inheritance of Fanconi anemia complementation group B
Fanconi anemia is an autosomal recessive syndrome characterized by diverse clinical symptoms, hypersensitivity to DNA… (More)
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