Factor V

Known as: Factor Pi, Blood-coagulation factor V, Proaccelerin 
Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor V accomplishes… (More)
National Institutes of Health

Papers overview

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Highly Cited
2000
Highly Cited
2000
BACKGROUND Venous thromboembolism is a leading cause of morbidity and mortality during pregnancy and the puerperium. However, the… (More)
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Highly Cited
1997
Highly Cited
1997
In this study, we identified and characterized a novel secreted protein, the extracellular serine protease EspP, which is encoded… (More)
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Highly Cited
1997
Highly Cited
1997
Factor V Leiden (factor V Arg506Gln), the genetic defect underlying resistance to activated protein C, is the most common risk… (More)
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Highly Cited
1995
Highly Cited
1995
We have analysed 3380 chromosomes (1690 unrelated individuals) from twenty-four populations for the presence of factor V Leiden… (More)
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Highly Cited
1995
Highly Cited
1995
Resistance to activated protein C (APC) is a common inherited risk factor for venous thrombosis, which is associated with a… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND A specific point mutation in the gene coding for coagulation factor V is associated with resistance to degradation by… (More)
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Highly Cited
1994
Highly Cited
1994
The cleavage of human factor V and human factor Va by human activated protein C (APC) was analyzed in the absence and presence of… (More)
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Highly Cited
1990
Highly Cited
1990
The activation of human factor V by factor Xa and thrombin was studied by functional assessment of cofactor activity and sodium… (More)
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Highly Cited
1979
Highly Cited
1979
The rates of prothrombin activation under initial conditions of invariant concentrations of prothrombin and Factor Xa were… (More)
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