FZD4 wt Allele

Known as: Fz4, FzE4, Frizzled 4, Seven Transmembrane Spanning Receptor Gene 
Human FZD4 wild-type allele is located in the vicinity of 11q14.2 and is approximately 10 kb in length. This allele, which encodes frizzled-4 protein… (More)

Topic mentions per year

Topic mentions per year

1983-2017
05101519832017

Papers overview

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Highly Cited
2012
Highly Cited
2012
Norrin/Frizzled4 (Fz4) signaling activates the canonical Wnt pathway to control retinal vascular development. Using genetically… (More)
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Highly Cited
2010
Highly Cited
2010
Familial exudative vitreoretinopathy (FEVR) is a genetically heterogeneous retinal disorder characterized by abnormal… (More)
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Highly Cited
2010
Highly Cited
2010
Familial exudative vitreoretinopathy (FEVR) is an inherited blinding disorder of the retinal vascular system. Although mutations… (More)
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Highly Cited
2009
Highly Cited
2009
Disorders of vascular structure and function play a central role in a wide variety of CNS diseases. Mutations in the Frizzled-4… (More)
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Highly Cited
2004
Highly Cited
2004
Familial exudative vitreoretinopathy (FEVR) is an inherited blinding disorder of the retinal vascular system. Autosomal dominant… (More)
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Highly Cited
2004
Highly Cited
2004
nt signalling pathways regulate cell proliferation, cell fate and morphogenetic movements. Here, we demonstrate that the Frizzled… (More)
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Highly Cited
2003
Highly Cited
2003
Wnt proteins, regulators of development in many organisms, bind to seven transmembrane-spanning (7TMS) receptors called frizzleds… (More)
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2003
2003
AIMS To search for mutations in the frizzled 4 (FZD4) gene in patients with familial exudative vitreoretinopathy (FEVR) and to… (More)
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Highly Cited
2002
Highly Cited
2002
Familial exudative vitreoretinopathy (FEVR) is a hereditary ocular disorder characterized by a failure of peripheral retinal… (More)
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Highly Cited
1993
Highly Cited
1993
Familial exudative vitreoretinopathy (FEVR) is a hereditary disorder characterized by an abnormality of the peripheral retina… (More)
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