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FUT4 gene

Known as: galactoside 3-L-fucosyltransferase, ALPHA-3-FUCOSYLTRANSFERASE, FUCOSYLTRANSFERASE 4 
This gene is involved in the generation of fucosylated carbohydrate structures.
National Institutes of Health

Related topics

Related topics

10 relations
FUT4 protein, humanFUT5 geneFUT6 geneFUT7 gene

Narrower (1)

FUT4 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4
The epithelial-mesenchymal transition (EMT) is an important factor in lung cancer metastasis, and targeting EMT is a potential… 
2015
2015
Baicalin promotes embryo adhesion and implantation by upregulating fucosyltransferase IV (FUT4) via Wnt/beta‐catenin signaling pathway
Highly Cited
2015
Highly Cited
2015
Ginsenoside Rg3-induced EGFR/MAPK pathway deactivation inhibits melanoma cell proliferation by decreasing FUT4/LeY expression
Malignant melanoma is a destructive and lethal form of skin cancer with poor prognosis. An effective treatment for melanoma is… 
Highly Cited
2014
Highly Cited
2014
Characterisation of FUT4 and FUT6 α-(1→2)-Fucosyltransferases Reveals that Absence of Root Arabinogalactan Fucosylation Increases Arabidopsis Root Growth Salt Sensitivity
Plant type II arabinogalactan (AG) polysaccharides are attached to arabinogalactan proteins (AGPs) at hydroxyproline residues… 
Highly Cited
2013
Highly Cited
2013
Role of fucosyltransferase IV in epithelial–mesenchymal transition in breast cancer cells
Epithelial–mesenchymal transition (EMT) is a crucial step in tumor progression and has an important role during cancer invasion… 
2010
2010
Overexpression of fucosyltransferase IV promotes A431 cell proliferation through activating MAPK and PI3K/Akt signaling pathways
Lewis Y (LeY) is a carbohydrate tumor‐asssociated antigen. The majority of cancer cells derived from epithelial tissue express… 
Highly Cited
2008
Highly Cited
2008
Suppression of FUT1/FUT4 expression by siRNA inhibits tumor growth.
Highly Cited
2006
Highly Cited
2006
Different expression levels of alpha3/4 fucosyltransferases and Lewis determinants in ovarian carcinoma tissues and cell lines.
Ovarian carcinoma is the leading cause of death from gynecological cancers in many countries. Fucosylated glycoconjugates have… 
Highly Cited
1998
Highly Cited
1998
Fucosyltransferase activities in human pancreatic tissue: comparative study between cancer tissues and established tumoral cell lines.
Human pancreatic cancer is characterized by an alteration in fucose-containing surface blood group antigens such as H antigen… 
1993
1993
Identification of the gene encoding the major capsid protein of fish lymphocystis disease virus.
The gene encoding the major capsid protein (MCP) of fish lymphocystis disease virus (flounder isolate; FLCDV-f) has been… 
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