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The neighbor-joining method: a new method for reconstructing phylogenetic trees.
The neighbor-joining method and Sattath and Tversky's method are shown to be generally better than the other methods for reconstructing phylogenetic trees from evolutionary distance data.
Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor.
Some synonymous mutations in the human DRD2 have functional effects and suggest a novel genetic mechanism, calling into question some assumptions made about synonymous variation in molecular population genetics and gene-mapping studies of diseases with complex inheritance, and indicate that synonymous variation can have effects of potential pathophysiological and pharmacogenetic importance.
Denisova admixture and the first modern human dispersals into Southeast Asia and Oceania.
Construction and Analysis of a Human-Chimpanzee Comparative Clone Map
A first-generation human-chimpanzee comparative genome map is presented and candidate positions, including two clusters on human chromosome 21 that suggest large, nonrandom regions of difference between the two genomes are detected.
DNA Data Bank of Japan (DDBJ) for genome scale research in life science
The DNA Data Bank of Japan (DDBJ) has made an effort to collect as much data as possible mainly from Japanese researchers, and developed the Genome Information Broker (GIB) and HGS, a database of the human genome, which have been updated incorporating newly available data and retrieval tools.
Evolutionary history of continental southeast Asians: "early train" hypothesis based on genetic analysis of mitochondrial and autosomal DNA data.
It is argued that both the mtDNA and autosomal data suggest an "Early Train" migration originating from Indochina or South China around the late-Pleistocene to early-Holocene period, which predates, but may not necessarily exclude, the Austronesian expansion.
Genetic origins of the Japanese: a partial support for the dual structure hypothesis.
A modified version of the dual structure model is proposed which may explain the genetic, morphological, and archaeological evidence concerning the formation of modern Japanese populations.
Relative Efficiencies of the Fitch-Margoliash, Maximum-Parsimony, Maximum-Likelihood, Minimum-Evolution, and Neighbor-joining Methods of Phylogenetic Tree Construction in Obtaining the Correct Tree
The relative efficiencies of several tree-making methods for obtaining the correct phylogenetic tree were studied by using computer simulation, and the NJ method seems to be a method of choice.
α1,3‐Fucoslytransferase IX (Fuc‐TIX) is very highly conserved between human and mouse; molecular cloning, characterization and tissue distribution of human Fuc‐TIX
Polymorphisms in the trace amine receptor 4 (TRAR4) gene on chromosome 6q23.2 are associated with susceptibility to schizophrenia.
- J. Duan, Maria Martinez, P. Gejman
- Psychology, BiologyAmerican journal of human genetics
- 1 October 2004
Genotyped 192 European-ancestry and African American pedigrees with schizophrenia from samples that previously showed linkage evidence to 6q13-q26, focusing on the MOXD1-STX7-TRARs gene cluster at 6q23.2, and revealed strong preliminary evidence that TRAR4 is a candidate gene for schizophrenia.