FUS protein, human

Known as: POMp75, hnRNP-P2, Fus-Like Protein 
RNA-binding protein FUS (526 aa, ~53 kDa) is encoded by the human FUS gene. This protein is involved in RNA processing, gene expression and genomic… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Approximately 70 human RNA-binding proteins (RBPs) contain a prion-like domain (PrLD). PrLDs are low-complexity domains that… (More)
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Highly Cited
2015
Highly Cited
2015
Many proteins contain disordered regions of low-sequence complexity, which cause aging-associated diseases because they are prone… (More)
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Highly Cited
2012
Highly Cited
2012
FUS/TLS (fused in sarcoma/translocated in liposarcoma) and TDP-43 are integrally involved in amyotrophic lateral sclerosis (ALS… (More)
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Highly Cited
2011
Highly Cited
2011
TDP-43 and FUS are RNA-binding proteins that form cytoplasmic inclusions in some forms of amyotrophic lateral sclerosis (ALS) and… (More)
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Review
2010
Review
2010
Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are neurodegenerative diseases with clinical and… (More)
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Review
2010
Review
2010
Abnormal intracellular protein aggregates comprise a key characteristic in most neurodegenerative diseases, including amyotrophic… (More)
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Highly Cited
2010
Highly Cited
2010
Mutations in fused in sarcoma (FUS) are a cause of familial amyotrophic lateral sclerosis (fALS). Patients carrying point… (More)
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Highly Cited
2009
Highly Cited
2009
Frontotemporal dementia (FTD) is a clinical syndrome with a heterogeneous molecular basis. The neuropathology associated with… (More)
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Review
2009
Review
2009
Mutations in TDP-43, a DNA/RNA-binding protein, cause an inherited form of the neurodegenerative disease amyotrophic lateral… (More)
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Highly Cited
2009
Highly Cited
2009
Amyotrophic lateral sclerosis (ALS) is a fatal degenerative motor neuron disorder. Ten percent of cases are inherited; most… (More)
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