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FUS protein, human

Known as: POMp75, hnRNP-P2, Fus-Like Protein 
RNA-binding protein FUS (526 aa, ~53 kDa) is encoded by the human FUS gene. This protein is involved in RNA processing, gene expression and genomic… 
National Institutes of Health

Related topics

Related topics

8 relations
Amyotrophic Lateral SclerosisFUS geneFUS wt AlleleGenes, Regulator

Broader (1)

RNA-Binding Protein FUS

Papers overview

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2017
2017
Long noncoding RNA SchLAH suppresses metastasis of hepatocellular carcinoma through interacting with fused in sarcoma
Emerging evidence has indicated that deregulation of long non‐coding RNAs (lncRNAs) can contribute to the progression and… 
2015
2015
The fused in sarcoma protein forms cytoplasmic aggregates in motor neurons derived from integration-free induced pluripotent stem cells generated from a patient with familial amyotrophic lateral…
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that primarily affects motor neurons (MNs) and has no… 
Highly Cited
2012
Highly Cited
2012
TDP-1/TDP-43 Regulates Stress Signaling and Age-Dependent Proteotoxicity in Caenorhabditis elegans
TDP-43 is a multifunctional nucleic acid binding protein linked to several neurodegenerative diseases including Amyotrophic… 
2012
2012
Classification of familial amyotrophic lateral sclerosis by family history: effects on frequency of genes mutation
Objective To classify familial amyotrophic lateral sclerosis (FALS) on the base of family history, and to determine whether… 
Highly Cited
2011
Highly Cited
2011
C-terminal FUS/TLS mutations in familial and sporadic ALS in Germany
2011
2011
New neuropathological findings in Unverricht–Lundborg disease: neuronal intranuclear and cytoplasmic inclusions
Unverricht–Lundborg disease (EPM1A), also known as Baltic myoclonus, is the most common form of progressive myoclonic epilepsy… 
2010
2010
FALS with FUS mutation in Japan, with early onset, rapid progress and basophilic inclusion
Correction to: J Hum Genet 2010; 55, 252–254. doi:10.1038/jhg.2010.16; published online 12 March 2010 Since the publication of… 
2005
2005
Gene expression profile identifies a rare epithelioid variant case of pleomorphic liposarcoma carrying FUS‐CHOP transcript
Aims : To describe a tumour with morphological and immunophenotypic characteristics of epithelioid variant of pleomorphic… 
2002
2002
Expression of the FUS domain restores liposarcoma development in CHOP transgenic mice
Fusion proteins created by chromosomal abnormalities are key components of mesenchymal cancer development. The most common… 
1999
1999
Dual Transforming Activities of the FUS (TLS)-ERG Leukemia Fusion Protein Conferred by Two N-Terminal Domains of FUS (TLS)
ABSTRACT The FUS (TLS)-ERG chimeric protein associated with t(16;21)(p11;q22) acute myeloid leukemia is structurally similar to… 
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