FTY-720

Known as: FTY 720, FTY720 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
05019962018

Papers overview

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Highly Cited
2011
Highly Cited
2011
Sphingosine 1-phosphate (S1P), a lysophospholipid, has gained relevance to multiple sclerosis through the discovery of FTY720… (More)
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Highly Cited
2009
Highly Cited
2009
Lymphocyte recruitment and activation have been implicated in the progression of cerebral ischemia-reperfusion (I/R) injury, but… (More)
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Highly Cited
2009
Highly Cited
2009
Osteoclasts are the only somatic cells with bone-resorbing capacity and, as such, they have a critical role not only in normal… (More)
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Highly Cited
2008
Highly Cited
2008
The mechanism by which sphingosine-1-phosphate receptor-1 (S1P1) acts to promote lymphocyte egress from lymphoid organs is not… (More)
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Highly Cited
2004
Highly Cited
2004
FTY720 is an immunosuppressant that reduces circulating levels of naïve lymphocytes by increasing their localization and… (More)
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Highly Cited
2004
Highly Cited
2004
Our prior in vitro studies indicate that sphingosine 1-phosphate (S1P), a phospholipid angiogenic factor, produces endothelial… (More)
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Highly Cited
2004
Highly Cited
2004
The factors directing marginal zone B cells to the splenic marginal zone are not well understood. Here we report that FTY720, a… (More)
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Highly Cited
2003
Highly Cited
2003
FTY720, a potent immunosuppressive agent, is phosphorylated in vivo into FTY720-P, a high affinity agonist for sphingosine 1… (More)
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Highly Cited
2002
Highly Cited
2002
Immunosuppressant drugs such as cyclosporin have allowed widespread organ transplantation, but their utility remains limited by… (More)
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Highly Cited
1998
Highly Cited
1998
FTY720, given i.v. or orally at 0.03 mg/kg or more, significantly prolonged skin allograft survival in a dose-dependent manner… (More)
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