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FTY-720

Known as: FTY 720, FTY720 
 
National Institutes of Health

Papers overview

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Review
2013
Review
2013
Regulatory T (Treg) cells are a developmentally and functionally distinct T cell subpopulation that is engaged in sustaining… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Fingolimod (FTY720), a sphingosine-1-phosphate-receptor modulator that prevents lymphocyte egress from lymph nodes… Expand
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Review
2010
Review
2010
Fingolimod (FTY720) is a first-in-class orally bioavailable compound that has shown efficacy in advanced clinical trials for the… Expand
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Review
2010
Review
2010
The discovery of fingolimod (FTY720/Gilenya; Novartis), an orally active immunomodulatory drug, has opened up new approaches to… Expand
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Highly Cited
2010
Highly Cited
2010
Sphingosine 1-phosphate (S1P), a lysophospholipid, has gained relevance to multiple sclerosis through the discovery of FTY720… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Fingolimod (FTY720) is a new oral immunomodulating agent under evaluation for the treatment of relapsing multiple… Expand
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Highly Cited
2006
Highly Cited
2006
Cell-based diabetes therapy requires an abundant cell source. Here, we report reversal of diabetes for more than 100 d in… Expand
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Highly Cited
2004
Highly Cited
2004
FTY720 is an immunosuppressant that reduces circulating levels of naïve lymphocytes by increasing their localization and… Expand
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Highly Cited
2002
Highly Cited
2002
Blood lymphocyte numbers, essential for the development of efficient immune responses, are maintained by recirculation through… Expand
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Highly Cited
2002
Highly Cited
2002
Immunosuppressant drugs such as cyclosporin have allowed widespread organ transplantation, but their utility remains limited by… Expand
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