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Conventional multiple or microdissection testicular sperm extraction: a comparative study.
Microsurgical technique is safe and may improve SRR for TESE in a variety of patients with NOA, especially patients with heterogeneous testicular tubules.
Single nucleotide polymorphisms in the protamine-1 and -2 genes of fertile and infertile human male populations.
Analysis of the human protamine-1 and -2 gene sequences revealed four single nucleotide polymorphisms (SNPs) in the PRM1 coding region, which did not cause any amino acid substitutions, and one SNP in thePRM2 gene, which produced translation termination, which may result in male infertility due to haploinsufficiency of PRM2.
Excellent Long‐term Outcome of ABO‐Incompatible Living Donor Kidney Transplantation in Japan
Long‐term outcome in recipients of ABO‐incompatible living kidneys is excellent, and graft survival rates were significantly higher in patients 29 years or younger than in patients 30 years or older and in patients who received anticoagulation therapy than in those who did not receive such therapy.
Prediction of successful outcome of microdissection testicular sperm extraction in men with idiopathic nonobstructive azoospermia.
A formula to calculate the probability of successful outcome using noninvasive parameters without a preoperative testicular biopsy, which is a relatively invasive examination is developed and should be useful for doctors considering microdissection testicular sperm extraction for patients with NOA.
Modulation of androgen receptor transactivation by gelsolin: a newly identified androgen receptor coregulator.
Data suggest that the weak androgenic effect of HF may be amplified by increasing the amount of GSN after androgen ablation treatment, and blockage of the interaction between AR and GSN could become a potential therapeutic target for the treatment of prostate cancer.
Single-nucleotide polymorphisms and mutation analyses of the TNP1 and TNP2 genes of fertile and infertile human male populations.
This study shows specific variability in the transition nuclear protein genes (TNPs) of sterile male patients and analysis of the human TNP1 and TNP2 gene sequences revealed 5 amino acid substitution-causing single nucleotide polymorphisms (SNPs) in the open-reading frame of the T NP2 gene.
Prostate-specific transcription factor hPSE is translated only in normal prostate epithelial cells.
Immunohistochemistry and in situ hybridization analysis revealed that hPSE protein was translated in normal prostate glandular epithelial cells, but not in carcinoma cells with h PSE transcripts, suggesting that expression of hPSe is regulated translationally in prostate epithelial Cells and that hpsE protein is a candidate for a marker distinguishing normal cells from cancer cells in the prostate.
Potential mechanism for the effects of dexamethasone on growth of androgen-independent prostate cancer.
BACKGROUND Dexamethasone, a synthetic glucocorticoid, has clinical benefit in patients with hormone-refractory prostate cancer (HRPC), but the mechanisms responsible for its effects are unknown. The
Increased infiltration of tumor associated macrophages is associated with poor prognosis of bladder carcinoma in situ after intravesical bacillus Calmette-Guerin instillation.
The count of tumor associated macrophages infiltrating the cancer area is useful for predicting the response of bladder carcinoma in situ to intravesical bacillus Calmette-Guerin instillation before treatment initiation.
Malignant lymphoma of the kidney
Primary renal lymphoma (PRL) is a rare disease, making information including etiologic factors for PRL extremely limited, and research into these factors is extremely limited.