FR260330

National Institutes of Health

Papers overview

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2007

2007

New strategy for the antifibrotic therapy with oral administration of FR260330 (a selective inducible nitric oxide synthase inhibitor) in rat experimental liver cirrhosis.

Hitoshi Kikuchi, Tadashi Katsuramaki, +6 authors Koichi Hirata
Wound repair and regeneration : official…
2007

Inducible nitric oxide synthase (iNOS) activity is significantly elevated in viral hepatitis, alcoholic cirrhosis, and… (More)

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2006

2006

Effect of a novel inducible nitric oxide synthase inhibitor, FR260330, in prevention of renal ischemia/reperfusion injury in vervet monkeys.

Shijie Qi, Dasheng Xu, +6 authors Huifang Chen
Transplantation
2006

Cytotoxic nitric oxide (NO) is produced during ischemia/reperfusion (I/R) injury by the expression of inducible NO synthase (iNOS… (More)

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2006

2006

FK330, a novel inducible nitric oxide synthase inhibitor, prevents ischemia and reperfusion injury in rat liver transplantation.

Saburo Tsuchihashi, Fady M Kaldas, +6 authors Jerzy W. Kupiec-Weglinski
American journal of transplantation : official…
2006

Nitric oxide (NO), produced via inducible NO synthase (iNOS), is implicated in the pathophysiology of liver ischemia/reperfusion… (More)

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2005

2005

Pharmacological profile of FR260330, a novel orally active inducible nitric oxide synthase inhibitor.

Noboru Chida, Yoshimi Hirasawa, +4 authors Seitaro Mutoh
European journal of pharmacology
2005

In this study, we examined effects of a newly synthesized chemical compound, FR260330, (2E)-3-(4-chlorophenyl)-N-[(1S)-2-oxo-2… (More)

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2005

2005

Nuclear factor-kappaB decoy oligodeoxynucleotides prevent acute lung injury in mice with cecal ligation and puncture-induced sepsis.

Naoyuki Matsuda, Yuichi Hattori, Subrina Jesmin, Satoshi Gando
Molecular pharmacology
2005

The transcription factor nuclear factor-kappaB (NF-kappaB) plays a key role in expression of many inflammatory genes responsible… (More)

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2005

2005

Effect of a novel inducible nitric oxide synthase inhibitor in prevention of rat chronic aortic rejections.

Jun Ouyang, Dasheng Xu, +8 authors Huifang Chen
Transplantation
2005

BACKGROUND Cytotoxic nitric oxide (NO) is produced during ischemia-reperfusion injury and acute and chronic rejection in… (More)

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