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FR 171113

Known as: FR-171113, FR171113 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

BenzamidesThiazolidines

Papers overview

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2014
2014
Advanced glycation end products potentiate citrated plasma-evoked oxidative and inflammatory reactions in endothelial cells by up-regulating protease-activated receptor-1 expression
Advanced glycation end products (AGEs) and receptor RAGE interaction contribute to endothelial cell damage in diabetes. Several… Expand
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2014
2014
Apixaban exerts anti-inflammatory effects in mesangial cells by blocking thrombin/protease-activated receptor-1 system.
Atrial fibrillation (AF) is most frequent arrhythmia in patients with chronic kidney disease (CKD) [1,2]. Since diabetes and… Expand
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2014
2014
Thrombin Mediates Vagal Apoptosis and Dysfunction in Inflammatory Bowel Disease
BackgroundIn inflammatory bowel disease, autonomic dysfunction contributes to symptoms, morbidity, and health care resource… Expand
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2014
2014
In vitro inhibition of protease-activated receptors 1, 2 and 4 demonstrates that these receptors are not involved in an Acanthamoeba castellanii keratitis isolate-mediated disruption of the human…
Granulomatous amoebic encephalitis is a rare but serious human disease leading almost always to death. The pathophysiology of… Expand
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2006
2006
Thrombin-induced delayed injury involves multiple and distinct signaling pathways in the cerebral cortex and the striatum in organotypic slice cultures
Thrombin, a serine protease essential for blood coagulation, also plays an important role in cellular injury associated with… Expand
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Highly Cited
2003
Highly Cited
2003
Inhibition of arterial thrombosis by a protease-activated receptor 1 antagonist, FR171113, in the guinea pig.
The antiplatelet and antithrombotic effects of FR171113, 3-(4-chlorophenyl)-2-(2,4-dichlorobenzoylimino)-5-(methoxycarbonyl… Expand
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1999
1999
In vitro antiplatelet profile of FR171113, a novel non-peptide thrombin receptor antagonist.
Synthetic peptides (5 to 14 amino acids), identical in sequence to the new amino-terminus of the thrombin receptor generated… Expand
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