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FK778

Known as: FK 778, FK-778 
 
National Institutes of Health

Papers overview

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2010
2010
BACKGROUND BK polyomavirus infection has been reported in 10% to 60% of renal transplant recipients with progression to BK… Expand
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2005
2005
FK778 (Fujisawa Healthcare Inc.) is an immunosuppressant structurally similar to A771726, the active metabolite of leflunomide… Expand
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2005
2005
BACKGROUND FK778 is a malononitrilamide, a class of immune suppressive compounds with antiviral features and experimental… Expand
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2004
2004
BACKGROUND In animal and in vitro models, FK778 inhibits acute rejection, modifies vasculopathy, and shows anti-viral activity… Expand
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2003
2003
BACKGROUND The leflunomide analog, FK778, is a selective pyrimidine synthesis inhibitor. In rodent models, FK778 is efficacious… Expand
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2003
2003
BACKGROUND Malononitrilamide 715 (FK778) is a new class of low-molecular-weight immunosuppressant that is a derivative of the… Expand
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2003
2003
BACKGROUND The effects of tacrolimus (FK506) and malononitrilamides (MNA) (FK778 and FK779) monotherapy and combination therapy… Expand
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2003
2003
BACKGROUND Leflunomide (LFM) inhibits experimentally both acute and chronic allograft rejection. The inhibition of dihydroorotate… Expand
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2003
2003
BACKGROUND FK778 is a new derivative of the active leflunomide metabolite A77 1726. It effectively prevented acute allograft… Expand
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2002
2002
BACKGROUND Leflunomide and its metabolite, A77 1726, interfere with pyrimidine metabolism and exert potent immunosuppression in… Expand
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