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FIRRE gene

Known as: firre intergenic repeating RNA element, functional intergenic repeating RNA element, FIRRE 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
A TAD boundary is preserved upon deletion of the CTCF-rich Firre locus
The binding of the transcriptional regulator CTCF to the genome has been implicated in the formation of topologically associated… Expand
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2018
2018
LncRNA FIRRE/NF-kB feedback loop contributes to OGD/R injury of cerebral microglial cells.
Stroke is one of the leading causes for serious long-term neurological disability. LncRNAs have been investigated to be… Expand
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2018
2018
Analysis of human ES cell differentiation establishes that the dominant isoforms of the lncRNAs RMST and FIRRE are circular
BackgroundCircular RNAs (circRNAs) are predominantly derived from protein coding genes, and some can act as microRNA sponges or… Expand
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2017
2017
The NF-κB–Responsive Long Noncoding RNA FIRRE Regulates Posttranscriptional Regulation of Inflammatory Gene Expression through Interacting with hnRNPU
Long noncoding RNAs, a newly identified class of noncoding RNAs, are important regulators of gene expression in innate immunity… Expand
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2016
2016
Function and evolution of local repeats in the Firre locus
More than half the human and mouse genomes are comprised of repetitive sequences, such as transposable elements (TEs), which have… Expand
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Review
2016
Review
2016
"Cat's Cradling" the 3D Genome by the Act of LncRNA Transcription.
There is growing evidence that transcription and nuclear organization are tightly linked. Yet, whether transcription of thousands… Expand
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Highly Cited
2015
Highly Cited
2015
The lncRNA Firre anchors the inactive X chromosome to the nucleolus by binding CTCF and maintains H3K27me3 methylation
BackgroundIn mammals, X chromosome genes are present in one copy in males and two in females. To balance the dosage of X-linked… Expand
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Highly Cited
2015
Highly Cited
2015
Long non-coding RNA LINC01296 is a potential prognostic biomarker in patients with colorectal cancer
Colorectal cancer (CRC), one of the most malignant cancers, is currently the fourth leading cause of cancer deaths worldwide… Expand
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Highly Cited
2015
Highly Cited
2015
Regulation of the ESC transcriptome by nuclear long noncoding RNAs.
Long noncoding (lnc)RNAs have recently emerged as key regulators of gene expression. Here, we performed high-depth poly(A)(+) RNA… Expand
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Highly Cited
2014
Highly Cited
2014
Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre
RNA, including long noncoding RNA (lncRNA), is known to be an abundant and important structural component of the nuclear matrix… Expand
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