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FIG4 wt Allele

Known as: FIG4 Homolog (S. cerevisiae) Gene, CMT4J, FIG4, S. cerevisiae, Homolog of Gene 
Human FIG4 wild-type allele is located in the vicinity of 6q21 and is approximately 134 kb in length. This allele, which encodes polyphosphoinositide… 
National Institutes of Health

Related topics

Related topics

3 relations
DephosphorylationHydrolysisPhospholipid Metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
FIG4 regulates lysosome membrane homeostasis independent of phosphatase function.
FIG4 is a phosphoinositide phosphatase that is mutated in several diseases including Charcot-Marie-Tooth Disease 4J (CMT4J) and… 
2013
2013
Gene-Specific DNA Methylation Association with Serum Levels of C-Reactive Protein in African Americans
A more thorough understanding of the differences in DNA methylation (DNAm) profiles in populations may hold promise for… 
2013
2013
Novel FIG4 mutations in Yunis–Varon syndrome
Yunis–Varon syndrome (YVS, MIM 216340) is a rare autosomal recessive disorder characterized by skeletal abnormalities and severe… 
Review
2012
Review
2012
PIKfyve and its Lipid products in health and in sickness.
PIKfyve, a phosphoinositide 5-kinase synthesizing PtdIns(3,5)P₂ and PtdIns5P in a cellular context, belongs to an evolutionarily… 
2009
2009
PIKfyve-ArPIKfyve-Sac3 Core Complex
The phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) metabolizing enzymes, the kinase PIKfyve and the phosphatase Sac3… 
Highly Cited
2007
Highly Cited
2007
Sus1, Sac3, and Thp1 mediate post-transcriptional tethering of active genes to the nuclear rim as well as to non-nascent mRNP.
Errors in the mRNP biogenesis pathway can lead to retention of mRNA in discrete, transcription-site-proximal foci. This RNA… 
Highly Cited
2003
Highly Cited
2003
Sac3 is an mRNA export factor that localizes to cytoplasmic fibrils of nuclear pore complex.
In eukaryotes, mRNAs are transcribed in the nucleus and exported to the cytoplasm for translation to occur. Messenger RNAs… 
2000
2000
Yunis-Varon syndrome: evidence for a lysosomal storage disease.
We present clinical and neuropathological findings in a female infant with Yunis-Varon syndrome (YVS) comprising absence of… 
Review
1998
Review
1998
Identification and Characterization of an Essential Family of Inositol Polyphosphate 5-Phosphatases ( INP 51 , INP 52 and INP 53 Gene Products ) in the Yeast Saccharomyces cerevisiae
We recently demonstrated that the S. cerevisiae INP51 locus (YIL002c) encodes an inositol polyphosphate 5-phosphatase. Here we… 
1996
1996
The SAC3 gene encodes a nuclear protein required for normal progression of mitosis.
The SAC3 gene of Saccharomyces serevisiae has been implicated in actin function by genetic experiments showing that a temperature… 
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