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FIG4 gene

Known as: CMT4J, SAC DOMAIN-CONTAINING INOSITOL PHOSPHATASE 3, hSac3 
This gene plays a role in the metabolism of polyphosphoinositides.
National Institutes of Health

Related topics

Related topics

4 relations
DephosphorylationHydrolysisPhospholipid Metabolismpolyphosphoinositide phosphatase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Identification of CR43467 encoding a long non-coding RNA as a novel genetic interactant with dFIG4, a CMT-causing gene.
2016
2016
FIG4 is a hepatitis C virus particle-bound protein implicated in virion morphogenesis and infectivity with cholesteryl ester modulation potential.
There is growing evidence that virus particles also contain host cell proteins, which provide viruses with certain properties… 
2016
2016
Identification of ppk18 and CR18854 as genetic interactants with Drosophila FIG4 , a CMT-causing and ALS-susceptibility gene
2016
2016
A cell-permeable tool for analysing APP intracellular domain function and manipulation of PIKfyve activity
In this work we developed and validated a cell permeable tool to study the intracellular function of a central molecule in… 
2013
2013
Murine Fig4 is dispensable for muscle development but required for muscle function
Phosphatidylinositol phosphates (PIPs) are low-abundance phospholipids that participate in a range of cellular processes… 
2012
2012
P41 Genetic analysis of FIG4 in patients with CMT
2008
2008
CMT4J: Charcot–Marie–Tooth disorder caused by mutations in FIG4
Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J
Chow et al. (2007)
Nature 448: 68–72… 
2007
2007
FIG4, Charcot‐Marie‐Tooth disease, and hypopigmentation: a role for phosphoinositides in melanosome biogenesis?
Pigmentation defects in mice and humans result from mutations in any of over 120 genes, many of which also influence additional… 
2004
2004
Characterization of novel Sac domain-containing lipid phosphatases (KIAA0274)
Review
2002
Review
2002
Structure and Evolution of the Actin Gene Family in Arabidopsis thalianu
Higher plants contain families of actin-encoding genes that are divergent and differentially expressed. Progress in understanding… 
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