FIG4 gene

Known as: CMT4J, SAC DOMAIN-CONTAINING INOSITOL PHOSPHATASE 3, hSac3 
This gene plays a role in the metabolism of polyphosphoinositides.

Topic mentions per year

Topic mentions per year

1989-2017
051019892017

Papers overview

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2014
2014
OBJECTIVE The aim of this study was to identify the causal gene in a consanguineous Moroccan family with temporo-occipital… (More)
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2011
2011
Loss of function of the FIG4 gene causes Charcot-Marie-Tooth disease (CMT)-4J with many features also found in motor neuron… (More)
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2011
2011
Charcot-Marie-Tooth disease is a genetically heterogeneous group of motor and sensory neuropathies associated with mutations in… (More)
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2011
2011
CMT4J is a severe form of Charcot-Marie-Tooth neuropathy caused by mutation of the phosphoinositide phosphatase FIG4/SAC3… (More)
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Highly Cited
2009
Highly Cited
2009
Mutations of the lipid phosphatase FIG4 that regulates PI(3,5)P(2) are responsible for the recessive peripheral-nerve disorder… (More)
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2008
2008
Recessive Charcot-Marie-Tooth disease type-4J (CMT4J) and its animal model, the pale tremor mouse (plt), are caused by mutations… (More)
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Highly Cited
2007
Highly Cited
2007
Membrane-bound phosphoinositides are signalling molecules that have a key role in vesicle trafficking in eukaryotic cells… (More)
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2003
2003
In eukaryotes, mRNAs are transcribed in the nucleus and exported to the cytoplasm for translation to occur. Messenger RNAs… (More)
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2002
2002
The Saccharomyces cerevisiae FAB1 gene encodes the sole phosphatidylinositol 3-phosphate [PtdIns(3)P] 5-kinase responsible for… (More)
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Highly Cited
1998
Highly Cited
1998
Yeast cells mate by an inducible pathway that involves agglutination, mating projection formation, cell fusion, and nuclear… (More)
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