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BACKGROUND. Understanding the genetic architecture of cardiac structure and function may help to prevent and treat heart disease… Expand Amyotrophic lateral sclerosis (ALS) is a devastating and still untreatable motor neuron disease. Despite the molecular mechanisms… Expand The single-nucleotide polymorphisms (SNPs) rs6700125 and rs6690993 in FGGY (FLJ10986) were recently reported to be a… Expand A recent genome-wide association study (GWAS) found significant association of six single nucleotide polymorphisms (SNPs) in the… Expand Function diversification in large protein families is a major mechanism driving expansion of cellular networks, providing… Expand Abstract DPP6 and FGGY genes have been recently associated with an increased susceptibility for sporadic amyotrophic lateral… Expand Respiratory sensitization is a concern for occupational and environmental health in consumer product development. Despite… Expand A genome-wide association study (GWAS) using pooled DNA samples from 386 sporadic ALS patients and 542 controls from the USA… Expand The cause of sporadic amyotrophic lateral sclerosis (ALS) is largely unknown, but genetic factors are thought to play a… Expand BACKGROUND
Approximately 90% of persons with amyotrophic lateral sclerosis (ALS) have the sporadic form, which may be caused by… Expand