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FGFR Inhibition

Known as: Fibroblastic Growth Factor Receptor Inhibition 
Inhibition of fibroblastic growth factor receptor signaling pathway activity to prevent tumor growth.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Treatments that use a pan-FGFR (fibroblast growth factor receptor) inhibitor plus anti–PD-1 can boost antitumor responses in… Expand
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2018
2018
Genetic alterations in the fibroblast growth factor receptors (FGFRs) have been described in multiple solid tumours including… Expand
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2017
2017
Lung squamous cell carcinoma (SqCC) is a molecularly complex and genomically unstable disease. No targeted therapy is currently… Expand
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2017
2017
Activating mutations and translocations of the FGFR3 gene are commonly seen in urothelial cell carcinoma (UCC) of the bladder and… Expand
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2016
2016
Introduction. Head and neck squamous cell carcinomas (HNSCCs) account for nearly 600,000 deaths worldwide annually and have… Expand
Highly Cited
2016
Highly Cited
2016
UNLABELLED FGFR1 and FGFR2 are amplified in many tumor types, yet what determines response to FGFR inhibition in amplified… Expand
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2015
2015
Myxoid liposarcomas account for more than one third of liposarcomas and about 10% of all adult soft tissue sarcomas. The tumors… Expand
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2013
2013
Our laboratory has previously shown that some gefitinib-insensitive head and neck squamous cell carcinoma (HNSCC) cell lines… Expand
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Highly Cited
2013
Highly Cited
2013
Aberrant fibroblast growth factor (FGF) and FGF receptor (FGFR) system have been associated with breast cancer. The objectives of… Expand
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Highly Cited
2013
Highly Cited
2013
Fibroblast growth factor 23 (FGF23) is a circulating factor secreted by osteocytes that is essential for phosphate homeostasis… Expand