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FGFR Inhibition

Known as: Fibroblastic Growth Factor Receptor Inhibition 
Inhibition of fibroblastic growth factor receptor signaling pathway activity to prevent tumor growth.
National Institutes of Health

Papers overview

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2018
2018
Genetic alterations in the fibroblast growth factor receptors (FGFRs) have been described in multiple solid tumours including… Expand
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2017
2017
Lung squamous cell carcinoma (SqCC) is a molecularly complex and genomically unstable disease. No targeted therapy is currently… Expand
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2017
2017
Purpose: Despite intense research, treatment options for patients with mesothelioma are limited and offer only modest survival… Expand
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2017
2017
Activating mutations and translocations of the FGFR3 gene are commonly seen in urothelial cell carcinoma (UCC) of the bladder and… Expand
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2016
2016
Introduction. Head and neck squamous cell carcinomas (HNSCCs) account for nearly 600,000 deaths worldwide annually and have… Expand
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Highly Cited
2016
Highly Cited
2016
UNLABELLED FGFR1 and FGFR2 are amplified in many tumor types, yet what determines response to FGFR inhibition in amplified… Expand
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2015
2015
Myxoid liposarcomas account for more than one third of liposarcomas and about 10% of all adult soft tissue sarcomas. The tumors… Expand
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2013
2013
Our laboratory has previously shown that some gefitinib-insensitive head and neck squamous cell carcinoma (HNSCC) cell lines… Expand
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2013
2013
Aberrant fibroblast growth factor (FGF) and FGF receptor (FGFR) system have been associated with breast cancer. The objectives of… Expand
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Highly Cited
2013
Highly Cited
2013
Fibroblast growth factor 23 (FGF23) is a circulating factor secreted by osteocytes that is essential for phosphate homeostasis… Expand
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