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FER protein, human

Known as: FPS/FES-Related Tyrosine Kinase, Tyrosine Kinase 3, C-FER 
Tyrosine-protein kinase Fer (822 aa, ~95 kDa) is encoded by the human FER gene. This protein plays a role in tyrosine phosphorylation, receptor… 
National Institutes of Health

Related topics

Related topics

14 relations
Cell AdhesionCell Differentiation processCell ProliferationEnzyme Gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
FMS-Like Tyrosine Kinase 3 Ligand Treatment of Mice Aggravates Acute Lung Injury in Response to Streptococcus pneumoniae: Role of Pneumolysin
ABSTRACT FMS-like tyrosine kinase-3 ligand (Flt3L) is a dendritic cell (DC) growth and differentiation factor with potential in… 
Highly Cited
2011
Highly Cited
2011
Protein-tyrosine Phosphatase DEP-1 Controls Receptor Tyrosine Kinase FLT3 Signaling*
Fms-like tyrosine kinase 3 (FLT3) plays an important role in hematopoietic differentiation, and constitutively active FLT3 mutant… 
2011
2011
Interleukin-2 inhibits FMS-like tyrosine kinase 3 receptor ligand (flt3L)-dependent development and function of conventional and plasmacytoid dendritic cells
Steady-state development of plasmacytoid dendritic cells (pDCs) and conventional dendritic cells (cDCs) requires the ligand for… 
Review
2009
Review
2009
Discovery and development of aurora kinase inhibitors as anticancer agents.
The process of cell division or mitosis is highly complex and tightly regulated. During this phase of the cell cycle two… 
Review
2007
Review
2007
FLT3 kinase inhibitors in the management of acute myeloid leukemia.
FMS-like tyrosine kinase 3 (FLT3) is a receptor tyrosine kinase (TK) expressed by immature hematopoietic cells and is important… 
Review
2006
Review
2006
Molecular targeting therapy for renal cell carcinoma
Metastatic renal cell carcinoma (RCC) is currently one of the most treatment-resistant malignancies. However, significant… 
Highly Cited
2005
Highly Cited
2005
Enforced expression of an Flt3 internal tandem duplication in human CD34+ cells confers properties of self-renewal and enhanced erythropoiesis.
To investigate the role of constitutively active internal tandem duplication (ITD) mutants of the Fms-like tyrosine kinase 3… 
Highly Cited
2005
Highly Cited
2005
Predictions, synthetic strategy, and isolation of a linear tetrametallic triple-stranded lanthanide helicate.
[*] Dr. G. Bernardinelli Laboratory of X-ray Crystallography University of Geneva 24 Quai E. Ansermet, 1211 Geneva 4 (Switzerland… 
Highly Cited
2003
Highly Cited
2003
Selective Cytotoxic Mechanism of GTP-14564, a Novel Tyrosine Kinase Inhibitor in Leukemia Cells Expressing a Constitutively Active Fms-like Tyrosine Kinase 3 (FLT3)*
The receptor tyrosine kinase FLT3 is constitutively activated by an internal tandem duplication (ITD) mutation within the… 
Review
1999
Review
1999
Mechanisms of mutagenesis in mammalian cells. Application to human thyroid tumours.
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