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FER protein, human

Known as: FPS/FES-Related Tyrosine Kinase, Tyrosine Kinase 3, C-FER 
Tyrosine-protein kinase Fer (822 aa, ~95 kDa) is encoded by the human FER gene. This protein plays a role in tyrosine phosphorylation, receptor… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Genomic investigations of acute myeloid leukemia (AML) have demonstrated that several genes are recurrently mutated, leading to… Expand
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Highly Cited
2012
Highly Cited
2012
This phase 1b trial investigated several doses and schedules of midostaurin in combination with daunorubicin and cytarabine… Expand
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Highly Cited
2010
Highly Cited
2010
PURPOSE Mutations leading to constitutive activation of the FMS-like tyrosine kinase 3 receptor (FLT3) occur in blasts of 30% of… Expand
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Highly Cited
2010
Highly Cited
2010
In humans and mice, CD8α+ conventional dendritic cells are the primary source of interferon-λ released in response to the… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Mutations occur in several genes in cytogenetically normal acute myeloid leukemia (AML) cells: the nucleophosmin gene… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND A role of microRNAs in cancer has recently been recognized. However, little is known about the role of microRNAs in… Expand
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Highly Cited
2006
Highly Cited
2006
Tandutinib (MLN518/CT53518) is a novel quinazoline-based inhibitor of the type III receptor tyrosine kinases: FMS-like tyrosine… Expand
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Highly Cited
2005
Highly Cited
2005
We demonstrate that functional and phenotypic equivalents of mouse splenic CD8+ and CD8− conventional dendritic cell (cDC… Expand
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Review
2003
Review
2003
Normal haematopoietic cells use complex systems to control proliferation, differentiation and cell death. The control of… Expand
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Highly Cited
2000
Highly Cited
2000
The ligand for the receptor tyrosine kinase fms-like tyrosine kinase 3 (flt3), also referred to as fetal liver kinase-2 (flk-2… Expand
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