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FCRL4 protein, human

Known as: FcRH4, hIFGP2, FcR-Like Protein 4 
Fc receptor-like protein 4 (515 aa, ~57 kDa) is encoded by the human FCRL4 gene. This protein may be involved in B cell-mediated immune responses.
National Institutes of Health

Related topics

Related topics

11 relations
FCRL4 geneITIMImmunoglobulin C2-set DomainIntegral Membrane Proteins

Broader (1)

Fc Receptor

Papers overview

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2020
2020
Top Reads
IL-27 Decreases Renal Fibrosis See article p. 377 Cell-Specific Regulation by a Genetic Variant of Atg16L1 See article p. 414 BCG… 
2018
2018
Antibodies Encoded by FCRL4-Bearing Memory B Cells Preferentially Recognize Commensal Microbial Antigens
FCRL4, a low-affinity IgA Ab receptor with strong immunoregulatory potential, is an identifying feature of a tissue-based… 
2017
2017
AB0013 Is there immune disregulation in non-sjÖgren sicca syndrome? a study of blood lymphocyte subpopulations
Background A large number of patients with sicca syndrome not fulfilling Sjögren's syndrome (SS) classification criteria, present… 
2017
2017
AB0015 Capture of iga immune complexes and enrichment in iga ig gene expression both suggest a role for fcrl4+ b cells in the link between mucosal and joint inflammation
Background Increasing evidence points to the autoimmune process of rheumatoid arthritis (RA) originating at mucosal surfaces… 
2015
2015
Expression of B-cell-associated genes in peripheral blood mononuclear cells of patients with symptomatic pulmonary embolism.
The aim of the present study was to identify differentially expressed B‑cell‑associated genes in peripheral blood mononuclear… 
2014
2014
Rheumatoid arthritis: Are FcRL4+ B cells the next target for RA biologic therapy?
systemically expressed by B cells in healthy individuals, it is predominantly tonsillar. Scheel-Toellner’s latest study… 
2014
2014
A1.53 A novel pro-inflammatory B cell population in the rheumatoid synovium can be identified by expression of FCRL4
Background and Objectives The importance of B cells in the pathogenesis of rheumatoid arthritis (RA) is highlighted by the… 
2013
2013
Toll-like receptor B cell stimulation upregulates FcRL4 expression and FcRL4 amplification of TLR signaling is associated with hematopoietic cell kinase expression (P1374)
Fc receptor-like 4 (FcRL4) attenuates B-cell receptor signaling (BCR) while enhancing TLR-responsiveness. FcRL4-mediated BCR… 
2013
2013
OP0013 A Novel Pro-Inflammatory B Cell Population Infiltrating the Rheumatoid Synovium can be Identified by Expression of FCRL4
Background The importance of the B cell lineage in RA pathogenesis is highlighted by the clinical effectiveness of rituximab… 
2008
2008
A direct antigen-binding assay for detection of antibodies against native epitopes using alkaline phosphatase-tagged proteins.
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