FCGRT gene

Known as: Fc fragment of IgG receptor and transporter, Fc FRAGMENT OF IgG, RECEPTOR TRANSPORTER, ALPHA, IMMUNOGLOBULIN RECEPTOR, INTESTINAL, HEAVY CHAIN 
 
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Although it is known that FcRn, the neonatal Fc-receptor, functions to protect immune gamma globulin (IgG) from elimination, the… (More)
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Highly Cited
2007
Highly Cited
2007
The neonatal FcR (FcRn) is a receptor that protects IgG from catabolism and is important in maintaining high serum Ab levels. A… (More)
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Highly Cited
2007
Highly Cited
2007
The intracellular events on the recycling pathway that lead from sorting endosomes to exocytosis at the plasma membrane are… (More)
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Highly Cited
2006
Highly Cited
2006
We describe here the functional implications of an increase in IgG binding to the neonatal Fc receptor. We have defined in a… (More)
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Highly Cited
2004
Highly Cited
2004
The neonatal Fc receptor (FcRn) plays an important role in regulating the serum half-lives of IgG antibodies. A correlation has… (More)
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Highly Cited
2004
Highly Cited
2004
Administration of therapeutic proteins by methods other than injection is limited, in part, by inefficient penetration of… (More)
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Highly Cited
2001
Highly Cited
2001
Preclinical tests of therapeutic antibodies are frequently carried out in mice to evaluate pharmacokinetics and efficacy. However… (More)
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Highly Cited
2001
Highly Cited
2001
The transfer of maternal gamma-globulin (IgG) provides the neonate with humoral immunity during early life. In humans, maternal… (More)
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Review
1997
Review
1997
Recent data have indicated that the major histocompatibility complex (MHC) class I-related receptor FcRn plays a role in… (More)
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Highly Cited
1996
Highly Cited
1996
More than 30 years ago, Brambell published the hypothesis bearing his name [Brambell, F. W. R., Hemmings, W. A. & Morris, 1. C… (More)
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