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FBXW8 gene

Known as: FBW8, F-BOX AND WD40 DOMAIN PROTEIN 8, FBXW6 
 
National Institutes of Health

Related topics

Related topics

1 relation
F-Box Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
FBXW8-dependent degradation of MRFAP1 in anaphase controls mitotic cell death
Mof4 family associated protein 1 (MRFAP1) is a 14 kDa nuclear protein, which involves in maintaining normal histone modification… Expand
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Review
2016
Review
2016
The emerging roles of F-box proteins in pancreatic tumorigenesis.
The role of F-box proteins in pancreatic tumorigenesis is emerging owing to their pivotal and indispensable roles in cell… Expand
2014
2014
Evidence for a regulatory role of Cullin-RING E3 ubiquitin ligase 7 in insulin signaling.
Dysfunctional regulation of signaling pathways downstream of the insulin receptor plays a pivotal role in the pathogenesis of… Expand
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2014
2014
MicroRNA-218 inhibits the proliferation of human choriocarcinoma JEG-3 cell line by targeting Fbxw8.
MicroRNAs (miRNAs) are endogenous 19-25 nucleotide noncoding single-stranded RNAs that regulate gene expression by blocking the… Expand
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Highly Cited
2012
Highly Cited
2012
ATXN2-CAG42 Sequesters PABPC1 into Insolubility and Induces FBXW8 in Cerebellum of Old Ataxic Knock-In Mice
Spinocerebellar Ataxia Type 2 (SCA2) is caused by expansion of a polyglutamine encoding triplet repeat in the human ATXN2 gene… Expand
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Highly Cited
2007
Highly Cited
2007
PARC and CUL7 form atypical cullin RING ligase complexes.
CUL7 and the p53-associated, PARkin-like cytoplasmic protein (PARC) were previously reported to form homodimers and heterodimers… Expand
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Highly Cited
2006
Highly Cited
2006
A Critical Role for FBXW8 and MAPK in Cyclin D1 Degradation and Cancer Cell Proliferation
Cyclin D1 regulates G1 progression. Its transcriptional regulation is well understood. However, the mechanism underlying cyclin… Expand
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Highly Cited
2006
Highly Cited
2006
Fbxw8 Is Essential for Cul1-Cul7 Complex Formation and for Placental Development
ABSTRACT Cullin-based ubiquitin ligases (E3s) constitute one of the largest E3 families. Fbxw8 (also known as Fbw6 or Fbx29) is… Expand
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Highly Cited
2005
Highly Cited
2005
Identification of mutations in CUL7 in 3-M syndrome
Intrauterine growth retardation is caused by maternal, fetal or placental factors that result in impaired endovascular… Expand
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Highly Cited
2003
Highly Cited
2003
Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis
Cul1, a member of the cullin ubiquitin ligase family, forms a multiprotein complex known as SCF and plays an essential role in… Expand
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