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FBXW5 gene

Known as: F-box and WD repeat domain containing 5, DKFZP434B205, FBW5 
National Institutes of Health

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F-Box Proteins

Papers overview

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2014
2014
Tnfaip8 l1/Oxi‐β binds to FBXW5, increasing autophagy through activation of TSC2 in a Parkinson's disease model
Abnormal autophagy may contribute to neurodegeneration in Parkinson's disease (PD). However, it is largely unknown how autophagy… 
2013
2013
Tnfaip8l1/Oxi-β binds to FBXW5, increasing autophagy through activation of TSC2 in a Parkinson's disease model.
Abnormal autophagy may contribute to neurodegeneration in Parkinson's disease (PD). However, it is largely unknown how autophagy… 
Highly Cited
2011
Highly Cited
2011
The SCF–FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication
Deregulated centrosome duplication can result in genetic instability and contribute to tumorigenesis. Here, we show that… 
2011
2011
FBXW5 controls centrosome number
Regulatory mechanisms to prevent centriole overduplication during the cell cycle are not completely understood. In this issue… 
2009
2009
An F-box protein, FBXW5, negatively regulates TAK1 MAP3K in the IL-1beta signaling pathway.
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