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FAN1 gene

Known as: FANCD2/FANCI-Associated Nuclease 1 Gene, KIAA1018, FAN1 
This gene is involved in the regulation of DNA repair.
National Institutes of Health

Related topics

Related topics

4 relations
DNA RepairFanconi-Associated Nuclease 1dna binding

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FAN1 wt Allele

Papers overview

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2020
2020
Common variants in FAN1, located in 15q13.3, confer risk for schizophrenia and bipolar disorder in Han Chinese
2018
2018
Whole-Genome Sequence of Acetobacter orientalis Strain FAN1, Isolated from Caucasian Yogurt
ABSTRACT In traditional Caucasian yogurt, Acetobacter orientalis bacteria play important roles in the fermentation of milk in… 
2016
2016
Elucidating the molecular basis of Lynch-Like syndrome
Tesi realitzada a l'Institut d'Investigacio Biomedica de Bellvitge (IDIBELL) i a l'Institut Catala d'Oncologia (ICO) 
2016
2016
Interstitial Nephritis in Children
Tubulointerstitial nephritis (TIN) is an important cause of acute kidney injury. The two most common triggers are… 
2015
2015
The nuclease FAN1 is involved in DNA crosslink repair in Arabidopsis thaliana independently of the nuclease MUS81
Fanconi anemia is a severe genetic disorder. Mutations in one of several genes lead to defects in DNA crosslink (CL) repair in… 
2015
2015
The nuclease FAN 1 is involved in DNA crosslink repair in Arabidopsis thaliana independently of the nuclease MUS 81
Fanconi anemia is a severe genetic disorder. Mutations in one of several genes lead to defects in DNA crosslink (CL) repair in… 
2014
2014
Crystal structure of human Fanconi-associated nuclease 1
Dear Editor, DNA interstrand crosslinks (ICLs) are toxic to cells because they covalently link the two strands in the duplex… 
2013
2013
Therapeutics , Targets , and Chemical Biology EGFR-Activating Mutations Correlate with a Fanconi Anemia – likeCellular Phenotype That Includes PARP Inhibitor Sensitivity
In patients with lung cancer whose tumors harbor activating mutations in the EGF receptor (EGFR), increased responses to platinum… 
2010
2010
Human KIAA1018/FAN1 localizes to stalled replication forks via its ubiquitin-binding domain
Genome maintenance pathways correct aberrations in DNA that would be deleterious to the organism. A crucial element of many… 
2010
2010
DNA mismatch repair and chromatin & functional characterisation of the zinc finger of KIAA1018
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