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F 11782

Known as: F-11782 
National Institutes of Health

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1 relation

Broader (1)

tafluposide

Papers overview

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Review
2003
Review
2003
Dual topoisomerase I/II inhibitors in cancer therapy.
While the majority of topoisomerase (topo) inhibitors show selectivity against either topo I or topo II, a small class of… 
2003
2003
A dual mechanism of action of the anticancer agent F 11782 on human topoisomerase II alpha.
2003
2003
Apoptotic cell death induction by F 11782 a novel dual catalytic inhibitor of topoisomerases I and II.
2002
2002
Inhibition of nucleotide excision repair and sensitisation of cells to DNA cross-linking anticancer drugs by F 11782, a novel fluorinated epipodophylloid.
2000
2000
Characterization of DNA-strand breakage induced in V79 cells by F 11782, a catalytic inhibitor of topoisomerases
DNA damage induced in V79 cells by F 11782, or 2″,3″-bis pentafluorophenoxyacetyl-4′, 6′-ethylidene-β-D glucoside of 4′-phosphate… 
2000
2000
Preclinical antitumour activity of F 11782, a novel dual catalytic inhibitor of topoisomerases
F 11782 is a novel inhibitor of topoisomerases I and II, with an original mechanism of action (Perrin et al, 2000). This study… 
2000
2000
Detection of DNA-strand breaks in cells treated with F 11782, a catalytic inhibitor of topoisomerases I and II.
F 11782, or 2", 3"-bis pentafluorophenoxyacetyl-4',6'-ethylidene-beta-D glucoside of 4'-phosphate-4'-dimethylepipodophyllotoxin… 
Highly Cited
2000
Highly Cited
2000
F 11782, a novel epipodophylloid non-intercalating dual catalytic inhibitor of topoisomerases I and II with an original mechanism of action.
1999
1999
American Association for Cancer Research 1999: 10-14 April, Philadelphia, Pennsylvania.
No genuinely new targets or drugs were disclosed; instead, data about known therapeutic approaches and compounds were… 
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