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Extracellular Sulfatase Sulf-2

Known as: EC 3.1.6.-, SULF2, hSulf-2 
Extracellular sulfatase Sulf-2 (870 aa, ~100 kDa) is encoded by the human SULF2 gene. This protein plays a role in the removal of O-sulfate groups… 
National Institutes of Health

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8 relations
Enzyme GeneEsterase GeneHydrolaseHydrolysis

Papers overview

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2013
2013
Endosulfatases SULF1 and SULF2 limit Chlamydia muridarum infection
The first step in attachment of Chlamydia to host cells is thought to involve reversible binding to host heparan sulfate… 
2012
2012
Silencing of HSulf-2 expression in MCF10DCIS.com cells attenuate ductal carcinoma in situ progression to invasive ductal carcinoma in vivo
Ductal carcinoma in situ (DCIS) of the breast is a heterogeneous group of proliferative cellular lesions that have the potential… 
2010
2010
Evaluation of Extracellular Endosulfatase HSULF-2 in Breast Cancer Cell WNT Signaling and Its Inhibition by a Sulfate Ester Derivative of Synthetic Antioxidant
Abstract : The research results we obtained in this Army Concept grant include the following novel findings. A) We showed that 2… 
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