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Extracellular Sulfatase Sulf-2

Known as: EC 3.1.6.-, SULF2, hSulf-2 
Extracellular sulfatase Sulf-2 (870 aa, ~100 kDa) is encoded by the human SULF2 gene. This protein plays a role in the removal of O-sulfate groups… 
National Institutes of Health

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Enzyme GeneEsterase GeneHydrolaseHydrolysis

Papers overview

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2012
2012
Silencing of HSulf-2 expression in MCF10DCIS.com cells attenuate ductal carcinoma in situ progression to invasive ductal carcinoma in vivo
Ductal carcinoma in situ (DCIS) of the breast is a heterogeneous group of proliferative cellular lesions that have the potential… 
2010
2010
Evaluation of Extracellular Endosulfatase HSULF-2 in Breast Cancer Cell WNT Signaling and Its Inhibition by a Sulfate Ester Derivative of Synthetic Antioxidant
Abstract : The research results we obtained in this Army Concept grant include the following novel findings. A) We showed that 2… 
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