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Excision Repair Cross-Complementing Family

Known as: Excision Repair Cross-Complementing Protein Family, Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group Protein, Excision Repair Cross Complementing-Group 
A family of DNA repair proteins.
National Institutes of Health

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DNA Repair

Papers overview

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Review
2015
Review
2015
Research progress on the multidrug resistance mechanisms of osteosarcoma chemotherapy and reversal
Osteosarcoma (OS) is the most common and aggressive primary malignant type of bone cancer in children and adolescents… 
Highly Cited
2014
Highly Cited
2014
ATR pathway inhibition is synthetically lethal in cancer cells with ERCC1 deficiency.
The DNA damage response kinase ATR and its effector kinase CHEK1 are required for cancer cells to survive oncogene-induced… 
Review
2011
Review
2011
ERCC1 and ERCC2 Polymorphisms Predict Clinical Outcomes of Oxaliplatin-Based Chemotherapies in Gastric and Colorectal Cancer: A Systemic Review and Meta-analysis
Purpose: Nucleotide excision repair (NER) modulates platinum-based chemotherapeutic efficacy by removing drug-produced DNA damage… 
Highly Cited
2009
Highly Cited
2009
Hepatoprotective effect of Carissa carandas Linn root extract against CCl4 and paracetamol induced hepatic oxidative stress.
Oral pre-treatment with ethanolic extract of the roots of C. carandas (ERCC; 100, 200 and 400 mg/kg, po) showed significant… 
Highly Cited
2008
Highly Cited
2008
Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFIRI chemotherapy
The primary end point of the study was the analysis of associations between polymorphisms with putative influence on 5… 
Highly Cited
2003
Highly Cited
2003
ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes.
Highly Cited
2000
Highly Cited
2000
Reduced expression levels of nucleotide excision repair genes in lung cancer: a case-control analysis.
Epidemiological studies have indicated that reduced DNA repair capacity and increased DNA adduct levels are associated with… 
Highly Cited
1996
Highly Cited
1996
Sensitivity of CHO mutant cell lines with specific defects in nucleotide excision repair to different anti‐cancer agents
Nucleotide excision repair (NER) is one of the major DNA repair systems in mammalian cells, able to remove a broad spectrum of… 
Highly Cited
1993
Highly Cited
1993
Identical defects in DNA repair in xeroderma pigmentosum group G and rodent ERCC group 5
HUMANS with the complementation group G form of the inherited syndrome xeroderma pigmentosum (XP) are hypersensitive to solar… 
Highly Cited
1993
Highly Cited
1993
Structure and expression of the excision repair gene ERCC6, involved in the human disorder Cockayne's syndrome group B.
The human repair gene ERCC6--a presumed DNA (or RNA) helicase--has recently been found to function specifically in preferential… 
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