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Etomidate

Known as: Ethomidate, (R)-(+)-1-(alpha-Methylbenzyl)imidazole-5-carboxylic acid ethyl ester, (+)-etomidate 
An imidazole derivative with short-acting sedative, hypnotic, and general anesthetic properties. Etomidate appears to have gamma-aminobutyric acid… 
National Institutes of Health

Related topics

Related topics

27 relations
10 ML Etomidate 2 MG/ML Injection10 ML Etomidate 2 MG/ML Injection [Amidate]Brain IschemiaClosed head injuries

Narrower (8)

AmidateHypnomidateR 8110Radenarkon

Broader (2)

Anesthetics, IntravenousHypnotics and Sedatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2000
2000
Mice Lacking the Long Splice Variant of the γ2 Subunit of the GABAA Receptor Are More Sensitive to Benzodiazepines
Highly Cited
1993
Highly Cited
1993
Different inhibitory effect of etomidate and ketoconazole on the human adrenal steroid biosynthesis
SummaryThe narcotic agent etomidate and the antimycotic drug ketoconazole are known to block steroid biosynthesis in man. To… 
Highly Cited
1991
Highly Cited
1991
Echocardiographic assessment of the haemodynamic effects of propofol: a comparison with etomidate and thiopentone
The haemodynamic effects of propofol (2 mg/kg), etomidate (0.2 mg/kg) and thiopentone (4 mg/kg) were studied in 30 ASA 1 and 2… 
Highly Cited
1986
Highly Cited
1986
Generalized grand mal seizure after recovery from uncomplicated fentanyl-etomidate anesthesia.
There have been a number of reports of seizure-like activity after fentanyl administration (14). These have been associated with… 
Highly Cited
1985
Highly Cited
1985
Radiation inactivation of brain [35S]t-butylbicyclophosphorothionate binding sites reveals complicated molecular arrangements of the GABA/benzodiazepine receptor chloride channel complex.
Highly Cited
1985
Highly Cited
1985
Peri‐operative endocrine effects of etomidate
This study investigated the effects of etomidate on endocrine responses to anaesthesia and surgery. Patients undergoing abdominal… 
1985
1985
Modulation of a GABA‐Ergic Inhibitory Circuit in the In Vitro Hippocampus by Etomidate Isomers
A pulse-paired stimulation technique was used to examine the in vitro effects of the isomers of etomidate on synaptic… 
Highly Cited
1984
Highly Cited
1984
Differential interactions of GABA agonists, depressant and convulsant drugs with [35S]-t-butylbicyclophosphorothionate binding sites in cortex and cerebellum
1984
1984
Barbiturates allosterically inhibit GABA antagonist and benzodiazepine inverse agonist binding.
Highly Cited
1979
Highly Cited
1979
Effects of some anti-epileptic, neuroleptic and gabaminergic drugs on convulsions induced by D,L-allyglycine
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