Etomidate

Known as: Ethomidate, (R)-(+)-1-(alpha-Methylbenzyl)imidazole-5-carboxylic acid ethyl ester, (+)-etomidate 
An imidazole derivative with short-acting sedative, hypnotic, and general anesthetic properties. Etomidate appears to have gamma-aminobutyric acid… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Use of etomidate in the critically ill is controversial due to its links with an inadequate response to corticotropin and… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND The administration of etomidate for rapid sequence induction (RSI) has been linked to subsequent adrenocortical… (More)
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Highly Cited
2007
Highly Cited
2007
To investigate the effect of one single bolus of etomidate used for intubation on adrenal function in children with meningococcal… (More)
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Highly Cited
2005
Highly Cited
2005
CONTEXT Adequate adrenal function is pivotal to survive meningococcal sepsis. OBJECTIVES The objective of the study was to… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND The authors hypothesized that myoclonus after etomidate is dose-related, could be suppressed when small doses of… (More)
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Highly Cited
1999
Highly Cited
1999
We compared the effects of single doses of etomidate and thiopentone on adrenocortical function in a randomised controlled… (More)
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Highly Cited
1997
Highly Cited
1997
The gamma-aminobutyric acid type A (GABAA) receptor is a transmitter-gated ion channel mediating the majority of fast inhibitory… (More)
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Highly Cited
1997
Highly Cited
1997
1. The GABA modulating and GABA-mimetic actions of the general anaesthetic etomidate were examined in voltage-clamp recordings… (More)
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Highly Cited
1992
Highly Cited
1992
Anesthetic induction with propofol commonly results in hypotension. This study explored potential mechanisms contributing to… (More)
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Highly Cited
1984
Highly Cited
1984
The use of the intravenous anesthetic etomidate for prolonged sedation has been associated with low levels of plasma cortisol and… (More)
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