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Etomidate

Known as: Ethomidate, (R)-(+)-1-(alpha-Methylbenzyl)imidazole-5-carboxylic acid ethyl ester, (+)-etomidate 
An imidazole derivative with short-acting sedative, hypnotic, and general anesthetic properties. Etomidate appears to have gamma-aminobutyric acid… 
National Institutes of Health

Related topics

Related topics

27 relations
10 ML Etomidate 2 MG/ML Injection10 ML Etomidate 2 MG/ML Injection [Amidate]Brain IschemiaClosed head injuries

Narrower (8)

AmidateHypnomidateR 8110Radenarkon

Broader (2)

Anesthetics, IntravenousHypnotics and Sedatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
The δ Subunit of γ-Aminobutyric Acid Type A Receptors Does Not Confer Sensitivity to Low Concentrations of Ethanol
GABAA receptors (GABAARs) are usually formed by α, β, and γ or δ subunits. Recently, δ-containing GABAARs expressed in Xenopus… 
Highly Cited
1999
Highly Cited
1999
Pharmacologic and Behavioral Responses of Inbred C57BL/6J and Strain 129/SvJ Mouse Lines
Highly Cited
1997
Highly Cited
1997
The interaction of the general anesthetic etomidate with the gamma-aminobutyric acid type A receptor is influenced by a single amino acid.
The gamma-aminobutyric acid type A (GABAA) receptor is a transmitter-gated ion channel mediating the majority of fast inhibitory… 
Highly Cited
1997
Highly Cited
1997
Subunit‐dependent interaction of the general anaesthetic etomidate with the γ‐aminobutyric acid type A receptor
The GABA modulating and GABA‐mimetic actions of the general anaesthetic etomidate were examined in voltage‐clamp recordings… 
Highly Cited
1996
Highly Cited
1996
Inotropic Effects of Propofol, Thiopental, Midazolam, Etomidate, and Ketamine on Isolated Human Atrial Muscle
Background Cardiovascular instability after intravenous induction of anesthesia may be explained partly by direct negative… 
Highly Cited
1995
Highly Cited
1995
The Comparative Effects of Methohexital, Propofol, and Etomidate for Electroconvulsive Therapy
The intravenous anesthetics which are commonly used for electroconvulsive therapy (ECT) possess dosedependent anticonvulsant… 
Review
1994
Review
1994
Therapy of Cushing's syndrome with steroid biosynthesis inhibitors
Highly Cited
1992
Highly Cited
1992
Sympathetic responses to induction of anesthesia in humans with propofol or etomidate.
Anesthetic induction with propofol commonly results in hypotension. This study explored potential mechanisms contributing to… 
Review
1983
Review
1983
Benzodiazepine-GABA receptor-ionophore complex Current concepts
Highly Cited
1978
Highly Cited
1978
Pharmacokinetics of Etomidate, a New Intravenous Anesthetic
Etomidate sulfate, 0.3 mg/kg, was administered intravenously to eight patients and venous blood samples were drawn at intervals… 
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