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Etomidate

Known as: Ethomidate, (R)-(+)-1-(alpha-Methylbenzyl)imidazole-5-carboxylic acid ethyl ester, (+)-etomidate 
An imidazole derivative with short-acting sedative, hypnotic, and general anesthetic properties. Etomidate appears to have gamma-aminobutyric acid… 
National Institutes of Health

Related topics

Related topics

27 relations
10 ML Etomidate 2 MG/ML Injection10 ML Etomidate 2 MG/ML Injection [Amidate]Brain IschemiaClosed head injuries

Narrower (8)

AmidateHypnomidateR 8110Radenarkon

Broader (2)

Anesthetics, IntravenousHypnotics and Sedatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2000
2000
Mice Lacking the Long Splice Variant of the γ2 Subunit of the GABAA Receptor Are More Sensitive to Benzodiazepines
Highly Cited
1993
Highly Cited
1993
A comparison of the cerebral protective effects of etomidate, thiopental, and isoflurane in a model of forebrain ischemia in the rat.
We evaluated the effect of etomidate, thiopental, and isoflurane on ischemic neuronal injury in rats. Control group animals… 
Highly Cited
1991
Highly Cited
1991
Echocardiographic assessment of the haemodynamic effects of propofol: a comparison with etomidate and thiopentone
The haemodynamic effects of propofol (2 mg/kg), etomidate (0.2 mg/kg) and thiopentone (4 mg/kg) were studied in 30 ASA 1 and 2… 
Highly Cited
1986
Highly Cited
1986
Generalized grand mal seizure after recovery from uncomplicated fentanyl-etomidate anesthesia.
There have been a number of reports of seizure-like activity after fentanyl administration (14). These have been associated with… 
Highly Cited
1985
Highly Cited
1985
Radiation inactivation of brain [35S]t-butylbicyclophosphorothionate binding sites reveals complicated molecular arrangements of the GABA/benzodiazepine receptor chloride channel complex.
Highly Cited
1985
Highly Cited
1985
Peri‐operative endocrine effects of etomidate
This study investigated the effects of etomidate on endocrine responses to anaesthesia and surgery. Patients undergoing abdominal… 
Highly Cited
1984
Highly Cited
1984
Differential interactions of GABA agonists, depressant and convulsant drugs with [35S]-t-butylbicyclophosphorothionate binding sites in cortex and cerebellum
1984
1984
Barbiturates allosterically inhibit GABA antagonist and benzodiazepine inverse agonist binding.
Highly Cited
1979
Highly Cited
1979
Effects of some anti-epileptic, neuroleptic and gabaminergic drugs on convulsions induced by D,L-allyglycine
Highly Cited
1975
Highly Cited
1975
Etomidate, a potent non-barbiturate hypnotic. Intravenous etomidate in mice, rats, guinea-pigs, rabbits and dogs.
Etomidate, R-(+)-ethyl-1-(1-phenylethyl)-1H-imidazole-5-carboxylate was found to be a potent, short-acting and safe hypnotic… 
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