ErbB-2 Inhibitor ARRY-380
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Tucatinib is a potent and selective oral HER2 tyrosine kinase inhibitor, with the potential to provide a well… (More)
Purpose: ONT-380 (ARRY-380) is a potent and selective oral HER2 inhibitor. This Phase I study determined the MTD… (More)
The clinical development of the HER2-specifi c monoclonal antibody trastuzumab is an oncology success story. Adding trastuzumab… (More)
The natural history of HER2-positive breast cancer has progressively improved since the introduction of the first anti-HER2… (More)