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Epoprostenol Sodium

Known as: Prosta-5,13-dien-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, Sodium salt, (5Z,9alpha,11alpha,13E,15S)-, Sodium(Z)-(3aR,4R,5R,6aS)-hexahydro-5-hydroxy-4-((E)-(3S)-3-hydroxy-1-octenyl)-2H-cyclopenta(b)furan-delta(sup 2,delta)-valerate, Epoprostenol Sodium [Chemical/Ingredient] 
The sodium salt form of epoprostenol, a synthetic prostacyclin, a member of the family of prostaglandins, with vasodilatory and anticoagulant… 
National Institutes of Health

Related topics

Related topics

18 relations
Arterial Vasodilation [PE]ArteriosclerosisCongestive heart failureDecreased Blood Pressure [PE]

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Papers overview

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2017
2017
Comparison of inhaled milrinone, nitric oxide and prostacyclin in acute respiratory distress syndrome
AIM To evaluate the safety and efficacy of inhaled milrinone in acute respiratory distress syndrome (ARDS). METHODS Open-label… 
Review
2015
Review
2015
Epoprostenol sodium for treatment of pulmonary arterial hypertension
The release of endogenous prostacyclin (PGI2) is depressed in patients with pulmonary arterial hypertension (PAH). PGI2… 
Review
2014
Review
2014
A Review of Inhaled Nitric Oxide and Aerosolized Epoprostenol in Acute Lung Injury or Acute Respiratory Distress Syndrome
Acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) are conditions associated with an estimated mortality of… 
2012
2012
Stability and microbiological properties of a new formulation of epoprostenol sodium when reconstituted and diluted
Purpose Epoprostenol, used for the treatment of pulmonary arterial hypertension (PAH), has a number of limitations related to its… 
2008
2008
Prostacyclin (epoprostenol) induces headache in healthy subjects
Highly Cited
2007
Highly Cited
2007
Bloodstream infections among patients treated with intravenous epoprostenol or intravenous treprostinil for pulmonary arterial hypertension--seven sites, United States, 2003-2006.
Pulmonary arterial hypertension (PAH) is a life-threatening disorder characterized by elevated pulmonary artery pressure and… 
Highly Cited
2001
Highly Cited
2001
Cardiac surgery with cardiopulmonary bypass in patients with type II heparin-induced thrombocytopenia.
1998
1998
Intrapulmonary shunting in primary pulmonary hypertension: an observation in two patients treated with epoprostenol sodium.
Continuous intravenous infusion of epoprostenol sodium in selected patients with primary pulmonary hypertension improves symptoms… 
Highly Cited
1996
Highly Cited
1996
Aerosolized Prostacyclin and Iloprost in Severe Pulmonary Hypertension
Primary pulmonary hypertension is a progressive fatal disease of unknown cause, and patients with this condition have a median… 
Review
1994
Review
1994
Intravenous prostacyclin (as epoprostenol) infusion in thrombotic thrombocytopenic purpura. Four case reports and review of the literature. Italian Cooperative Group for Thrombotic Thrombocytopenic…
BACKGROUND The enhanced platelet aggregation which is observed in TTP, was suggested to be due to an imbalance between unknown… 
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