Epithelium of pancreatic duct

Pancreatic ductal adenocarcinoma (PDAC) has one of the worst survival rates of all cancers. ANO1 (TMEM16A) is a recently… (More)

Mutational activation of KRas is the first and most frequently detected genetic lesion in pancreatic ductal adenocarcinoma (PDAC… (More)

OBJECTIVES Expression of transcription factors that mediate epithelial-mesenchymal transition (EMT), such as Twist and Slug, is… (More)

Recent reports suggest that bone marrow-derived cells engraft and differentiate into pancreatic tissue at very low frequency… (More)

OBJECTIVES Establishing more effective treatment of pancreatic cancer requires an understanding of the molecular events leading… (More)

The stimulatory pathways controlling HCO3- secretion by the pancreatic ductal epithelium are well described. However, only a few… (More)

A multistep model of carcinogenesis has recently been proposed for pancreatic ductal adenocarcinomas. In this model, noninvasive… (More)

In rats, a proportion of pancreatic beta-cells are deleted by apoptosis in the second week of postnatal life and replaced by… (More)

The purpose of this study was to characterize the trophic effect of pancreatic duct cells on the islets of Langerhans. Ductal… (More)

Recombinant tissue consisting of adult ductal epithelium isolated from pancreas and fetal mesenchyme was transplanted… (More)