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Epiregulin

Known as: Epiregulin [Chemical/Ingredient] 
A member of the epidermal growth factor (EGF) family of peptide growth factors that is synthesized as a transmembrane protein which can be cleaved to… 
National Institutes of Health

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Related topics

11 relations
EREG geneIn BloodProcess of secretionProepiregulin, human

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EREG protein, humanEreg protein, rat

Papers overview

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2007
2007
Epiregulin promotes proliferation and migration of renal proximal tubular cells.
Epiregulin is an epidermal growth factor (EGF) member that activates ErBB1 and ErBB4 homodimers and all possible heterodimeric… 
Highly Cited
2006
Highly Cited
2006
The aryl hydrocarbon receptor directly regulates expression of the potent mitogen epiregulin.
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is known to cause a large number of adverse effects, mediated largely by its binding… 
Highly Cited
2004
Highly Cited
2004
Expression of epiregulin and amphiregulin in the rat ovary.
We have previously reported that the epidermal growth factor (EGF) family growth factor, epiregulin, is expressed in rat ovarian… 
Highly Cited
2003
Highly Cited
2003
Epiregulin as a Major Autocrine/Paracrine Factor Released From ERK- and p38MAPK-Activated Vascular Smooth Muscle Cells
Background—The coordinated activation of extracellular signal–regulated kinase (ERK) and p38 mitogen-activated protein kinase… 
2003
2003
Factor Xa Induces Mitogenesis of Vascular Smooth Muscle Cells via Autocrine Production of Epiregulin*,*
Factor Xa has been reported to elicit smooth muscle cell proliferation via autocrine release of platelet-derived growth factor… 
2003
2003
Topical epiregulin enhances repair of murine excisional wounds
Epiregulin is a broad specificity epidermal growth factor family member that activates ErbB1 and ErbB4 homodimers and all… 
2002
2002
Transcriptional regulation of the epiregulin gene in the rat ovary.
Ovarian follicular development is initiated by FSH secreted from the pituitary gland. The FSH-induced follicular development… 
Highly Cited
2000
Highly Cited
2000
Involvement of deregulated epiregulin expression in tumorigenesis in vivo through activated Ki-Ras signaling pathway in human colon cancer cells.
To identify the genes located downstream of the activated Ki-Ras signaling pathways in human colon cancer cells, a PCR-based cDNA… 
Highly Cited
2000
Highly Cited
2000
Epiregulin is Up-regulated in pancreatic cancer and stimulates pancreatic cancer cell growth.
Epiregulin belongs to the epidermal growth factor (EGF) family of polypeptides. Previous studies have underscored the important… 
Highly Cited
1997
Highly Cited
1997
Distribution of mRNA for human epiregulin, a differentially expressed member of the epidermal growth factor family.
We have recently identified epiregulin as a new growth regulator and a member of the epidermal growth factor (EGF) family… 
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