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Ephrin Type-B Receptor 4, human

Known as: Ephrin Type-B Receptor 4, Tyrosine-Protein Kinase Receptor HTK, Tyrosine-Protein Kinase TYRO11 
Ephrin type-B receptor 4 (987 aa, ~108 kDa) is encoded by the human EPHB4 gene. This protein plays a role in ephrin-B binding, tyrosine… 
National Institutes of Health

Related topics

Related topics

24 relations
Angiogenic ProcessAxon GuidanceCell Differentiation processCell Proliferation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
In Vivo Small-Animal PET/CT of EphB4 Receptors Using 64Cu-Labeled Peptide
Many solid tumors overexpress EphB4 receptor, a member of the ephrin receptor tyrosine kinase family. Noninvasive imaging of… 
2010
2010
Converging Evidence for Efficacy from Parallel EphB4-Targeted Approaches in Ovarian Carcinoma
EphB4 is a transmembrane receptor tyrosine kinase that plays an important role in neural plasticity and angiogenesis. EphB4 is… 
2010
2010
Inhibitors of the tyrosine kinase EphB4. Part 3: identification of non-benzodioxole-based kinase inhibitors.
2010
2010
Of Ephs and ephrins: companies target guidance molecules in cancer.
E nzymes with the mysterious name of Ephs, which help the axons of neurons find their way forward during embryonic development… 
2009
2009
EPHB4 Gene Polymorphisms and Risk of Intracranial Hemorrhage in Patients With Brain Arteriovenous Malformations
Background— Brain arteriovenous malformations (BAVMs) are a tangle of abnormal vessels directly shunting blood from the arterial… 
2009
2009
Staurosporine augments EGF-mediated EMT in PMC42-LA cells through actin depolymerisation, focal contact size reduction and Snail1 induction – A model for cross-modulation
BackgroundA feature of epithelial to mesenchymal transition (EMT) relevant to tumour dissemination is the reorganization of actin… 
2008
2008
Cytochrome P450 2C9-Induced Angiogenesis Is Dependent on EphB4
Objective—Cytochrome P450 (CYP) epoxygenase-derived epoxyeicosatrienoic acids (EETs) are known to stimulate angiogenesis, but the… 
2007
2007
EphB4 Expression Along Adult Rat Microvascular Networks: EphB4 Is More Than a Venous Specific Marker
ABSTRACT 
2005
2005
Up-Regulation of EphB4 in Mesothelioma and Its Biological Significance
Purpose: Mesothelioma is a rare malignancy that is incurable and carries a short survival despite surgery, radiation, or… 
2004
2004
Syndecan-1 up-regulated by ephrinB2/EphB4 plays dual roles in inflammatory angiogenesis.
EphrinB2 and EphB4, its cognate receptor, are important in the vascular development of the mouse embryo. Their roles in human… 
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