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Ephrin-A4

Known as: Epl4 Protein, EPLG4, LERK 4 Protein 
A GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR containing ephrin found in variety of adult tissue such as KIDNEY; LUNG; COLON and OVARY. During… 
National Institutes of Health

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EFNA4 geneIn BloodProcess of secretionagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
A phase I study of PF-06647263, a novel EFNA4-ADC, in patients with metastatic triple negative breast cancer.
2511Background: PF-06647263 is an anti-Ephrin-A4 (EFNA4) antibody drug conjugate (ADC) composed of a humanized mAb, a hydrazone… 
2015
2015
Abstract 5425: An anti-Ephrin-A4 calicheamicin conjugate effectively targets triple-negative breast and ovarian tumor-initiating cells to result in sustained tumor regression
Triple-negative breast cancer (TNBC) and ovarian cancer comprise heterogeneous tumors, and neither targeted therapies nor… 
2012
2012
The platelet P2Y12 receptor contributes to granule secretion through Ephrin A4 receptor
The main responses of P2Y1 ligation are platelet shape change and transient aggregation while P2Y12 ligation amplifies P2Y1… 
2011
2011
[Inhibitory effect of chondroitinase ABC on ephrin A4 expression after spinal cord injury in rats].
The aim of the study was to investigate the effect of chondroitinase ABC (ChABC) on ephrin A4 (EphA4) expression after spinal… 
2009
2009
Immunohistochemical profile of ephrin A4 expression in human osteosarcoma
Ephrin receptors and ephrin ligands constitute one of the largest groups of tyrosine kinases. The division of ephrin receptors… 
2002
2002
Characterization of the human ephrin-A4 promoter.
Expression of the ephrin-A4 ligand, a family member of ligands binding the Eph receptor tyrosine kinases, is induced after an… 
1999
1999
Characterization of ephrin-A1 and ephrin-A4 as ligands for the EphA8 receptor protein tyrosine kinase.
1996
1996
The genes encoding the eph-related receptor tyrosine kinase ligands LERK-1 (EPLG1, Epl1), LERK-3 (EPLG3, Epl3), and LERK-4 (EPLG4, Epl4) are clustered on human chromosome 1 and mouse chromosome 3.
Hek and elk are members of the eph-related family of receptor tyrosine kinases. Recently, we isolated five cDNAs encoding… 
1995
1995
Ligands for EPH‐related tyrosine kinase receptors are developmentally regulated in the CNS
Elk is a member of the eph family of receptor‐like tyrosine kinases. Although its function is unknown, elk is postulated to play… 
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