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Eosinophil-Derived Neurotoxin

Known as: Eosinophil Protein X, RNS2 Neurotoxin, s-EPX 
A 19-kDa cationic peptide found in EOSINOPHIL granules. Eosinophil-derived neurotoxin is a RIBONUCLEASE and may play a role as an endogenous… Expand
National Institutes of Health

Related topics

Related topics

12 relations

Broader (2)

Immunologic FactorsNeurotoxins
In BloodProcess of secretionRNASE2 geneagonists
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Narrower (1)

RNASE2 protein, human

Papers overview

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Highly Cited
2010
Highly Cited
2010
Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines.
Nanotechnology is an innovative method of freely controlling nanometre-sized materials. Recent outbreaks of mucosal infectious… Expand
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Highly Cited
2008
Highly Cited
2008
Fecal markers of inflammation used as surrogate markers for treatment outcome in relapsing inflammatory bowel disease.
AIM To evaluate fecal calprotectin (FC) as a surrogate marker of treatment outcome of relapse of inflammatory bowel disease (IBD… Expand
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Highly Cited
2007
Highly Cited
2007
Production of the Neurotoxin BMAA by a Marine Cyanobacterium
Diverse species of cyanobacteria have recently been discovered to produce the neurotoxic non-protein amino acid β-methylamino-L… Expand
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Highly Cited
2002
Highly Cited
2002
Noradrenergic lesions differentially alter the antidepressant-like effects of reboxetine in a modified forced swim test.
The novel antidepressant reboxetine is a selective norepinephrine reuptake inhibitor. In this study, the antidepressant-like… Expand
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Review
2001
Review
2001
Eosinophils, eosinophil ribonucleases, and their role in host defense against respiratory virus pathogens.
Eosinophils remain among the most enigmatic of cells, as our appreciation of their detrimental activities--e.g., asthma and… Expand
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Highly Cited
2001
Highly Cited
2001
Extended exhaled NO measurement differentiates between alveolar and bronchial inflammation.
Lower respiratory tract inflammation can be detected by measuring exhaled nitric oxide (NO) concentration at a single exhalation… Expand
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Highly Cited
2000
Highly Cited
2000
Severe atopic dermatitis is associated with sensitization to staphylococcal enterotoxin B (SEB).
BACKGROUND Staphylococcus aureus has been identified as a possible trigger factor in atopic dermatitis (AD). Some 30-60% of S… Expand
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Highly Cited
1999
Highly Cited
1999
NO in exhaled air is correlated with markers of eosinophilic airway inflammation in corticosteroid-dependent childhood asthma.
The relationship between nitric oxide in exhaled air, levels of sputum eosinophils, sputum eosinophil cationic protein (ECP) and… Expand
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Highly Cited
1986
Highly Cited
1986
Biochemical and functional similarities between human eosinophil-derived neurotoxin and eosinophil cationic protein: homology with ribonuclease.
Eosinophil-derived neurotoxin (EDN) and eosinophil cationic protein (ECP) were isolated from lysates of human eosinophil granules… Expand
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Highly Cited
1981
Highly Cited
1981
Purification of human eosinophil-derived neurotoxin.
Human and animal eosinophils contain a powerful neurotoxin that causes selective neuronal and axonal damage to white matter of… Expand
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