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Eosinophil-Derived Neurotoxin

Known as: Eosinophil Protein X, RNS2 Neurotoxin, s-EPX 
A 19-kDa cationic peptide found in EOSINOPHIL granules. Eosinophil-derived neurotoxin is a RIBONUCLEASE and may play a role as an endogenous… 
National Institutes of Health

Related topics

Related topics

12 relations

Broader (2)

Immunologic FactorsNeurotoxins
In BloodProcess of secretionRNASE2 geneagonists

Narrower (1)

RNASE2 protein, human

Papers overview

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1998
1998
The 26‐mer peptide released from SNAP‐25 cleavage by botulinum neurotoxin E inhibits vesicle docking
Highly Cited
1997
Highly Cited
1997
Effect of a bed covering system in children with asthma and house dust mite hypersensitivity.
Allergen avoidance is regarded as an important approach to management of atopic asthma. The effect of Intervent bed covering… 
Highly Cited
1996
Highly Cited
1996
Mast cells mediate acid-induced augmentation of opossum esophageal blood flow via histamine and nitric oxide.
BACKGROUND & AIMS Increased esophageal blood flow during reflux episodes may play an important role in mucosal resistance to… 
1996
1996
Substitutions of Proline 42 to Alanine and Methionine 46 to Asparagine around the RGD Domain of the Neurotoxin Dendroaspin Alter Its Preferential Antagonism to That Resembling the Disintegrin…
Previous studies have shown that the neurotoxin dendroaspin and the disintegrin kistrin, which show little overall sequence… 
Highly Cited
1995
Highly Cited
1995
Increased Concentrations of the Neurotoxin 3‐Hydroxykynurenine in the Frontal Cortex of HIV‐1‐Positive Patients
Abstract: Human immunodeficiency virus (HIV)‐1‐associated dementia is a frequent consequence of HIV infection and is associated… 
Highly Cited
1995
Highly Cited
1995
Eosinophil cationic protein(ECP) and eosinophil protein X (EXP) concentrations in serum and bronchial lavage fluid in asthma. effect of prednisolone treatment.
Background Eoswinophil granule proteins may contribute to hyperresponsiveness in asthma. 
Highly Cited
1993
Highly Cited
1993
Total blood eosinophils, serum eosinophil cationic protein and eosinophil protein X in childhood asthma: relation to disease status and therapy
Blood eosinophils, and serum levels of the eosinophil proteins, eosinophil cationic protein (ECP) and eosinophil protein X (EPX… 
Highly Cited
1992
Highly Cited
1992
Endogenous calcitonin gene-related peptide mediates nonadrenergic noncholinergic depressor response to spinal cord stimulation in the pithed rat.
The role of endogenous calcitonin gene-related peptide (CGRP) in the nonadrenergic noncholinergic depressor response to spinal… 
Review
1987
Review
1987
Eosinophil activation in allergic disease.
The eosinophil granulocyte is a pro-inflammatory cell which in its granules contains an abundance of highly cytotoxic proteins… 
Highly Cited
1978
Highly Cited
1978
Effects of neonatal 5,7-dihydroxytryptamine treatment on the development of serotonin neurons and their transmitter metabolism.
The effects of neonatal treatment of rats, systemically, with the neurotoxin 5,7-di-hydroxytryptamine (5,7-HT) on the central 5… 
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