Enoximone

Known as: 2H-Imidazol-2-One, 1,3-Dihydro-4-Methyl-5-(4-(Methylthio)Benzoyl)-, Enoximone [Chemical/Ingredient], 4-Methyl-5-(p-(Methylthio)Benzoyl)-4-Imidazolin-2-One 
A selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity that does not cause changes in myocardial oxygen… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
OBJECTIVE Cardiogenic shock is the leading cause of death in patients hospitalized for acute myocardial infarction. The… (More)
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Highly Cited
2002
Highly Cited
2002
OBJECTIVE We compared the hemodynamic effects of dobutamine and enoximone administration before and after long-term beta-blocker… (More)
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2001
2001
OBJECTIVE To investigate the impact of dobutamine and enoximone on hepatosplanchnic perfusion and function in fluid-optimized… (More)
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1996
1996
OBJECTIVE To evaluate whether clonidine, enoximone, and enalaprilat reduce ischaemia-related myocardial cell damage in cardiac… (More)
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1994
1994
OBJECTIVES To determine the effects of enoximone on mortality and quality of life in patients with severe end stage heart failure… (More)
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1991
1991
In a parallel study design, 164 patients with New York Heart Association Functional class II or III heart failure were randomized… (More)
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Highly Cited
1990
Highly Cited
1990
A multicenter double-blind, randomized, placebo-controlled trial of oral enoximone, a phosphodiesterase inhibitor, was conducted… (More)
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Review
1990
Review
1990
Enoximone is an inotropic vasodilating agent. Its principal effects are positive inotropism and vasodilation, which are not… (More)
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1987
1987
Hemodynamics, blood gas values, and lung mechanics were investigated in 19 patients with decompensated COPD before and 30 and 60… (More)
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Highly Cited
1986
Highly Cited
1986
We have identified and highly purified a "low Km" cAMP phosphodiesterase from bovine cardiac muscle. This phosphodiesterase was… (More)
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