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Enoximone

Known as: 2H-Imidazol-2-One, 1,3-Dihydro-4-Methyl-5-(4-(Methylthio)Benzoyl)-, Enoximone [Chemical/Ingredient], 4-Methyl-5-(p-(Methylthio)Benzoyl)-4-Imidazolin-2-One 
A selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity that does not cause changes in myocardial oxygen… 
National Institutes of Health

Related topics

Related topics

13 relations

Broader (3)

Cardiotonic AgentsPhosphodiesterase 3 InhibitorsVasodilator Agents
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Narrower (3)

MDL-17,043Perfanenoximone sulfoxide

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1999
1999
Reduced inotropic support after aprotinin therapy during pediatric cardiac operations.
1997
1997
Trial of pulmonary artery banding: a diagnostic criterion for 'one-stage' arterial switch in simple transposition of the great arteries beyond the neonatal period.
1993
1993
Intravenous enoximone or dobutamine for severe heart failure after acute myocardial infarction: a randomized double-blind trial.
Intravenous infusions of enoximone or dobutamine were given, using a double dummy technique, in a randomized, double-blind study… 
1993
1993
Ca2+(-)dependent and Ca2+(-)independent vasorelaxation induced by cardiotonic phosphodiesterase inhibitors.
Review
1990
Review
1990
Pharmacokinetics and pharmacodynamics of phosphodiesterase-III inhibitors
Review
1990
Review
1990
Pharmacology and pharmacokinetics of enoximone.
Enoximone is an inotropic vasodilating agent. Its principal effects are positive inotropism and vasodilation, which are not… 
Highly Cited
1989
Highly Cited
1989
Myocardial energetics in patients with dilated cardiomyopathy. Influence of nitroprusside and enoximone.
Cardiotonic agents influence myocardial energy consumption by vasodilation, which may reduce energy demand, and by inotropism… 
Highly Cited
1989
Highly Cited
1989
Effect of phosphodiesterase inhibition on myocardial oxygen consumption and coronary blood flow.
Highly Cited
1988
Highly Cited
1988
Do positive inotropic agents adversely affect the survival of patients with chronic congestive heart failure? I. Introduction.
Highly Cited
1985
Highly Cited
1985
Inotropic therapy for refractory congestive heart failure with oral fenoximone (MDL-17,043): poor long-term results despite early hemodynamic and clinical improvement.
Thirteen male patients with NYHA class IV congestive heart failure refractory to conventional therapy were treated with oral… 
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