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Endosomal Sorting Complexes Required for Transport

Known as: Complexes, ESCRT, ESCRT Machinery, ESCRT Complexes 
A set of protein subcomplexes involved in PROTEIN SORTING of UBIQUITINATED PROTEINS into intraluminal vesicles of MULTIVESICULAR BODIES and in… 
National Institutes of Health

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Narrower (19)

BROX protein, humanCHMP3 protein, humanCHMP7 protein, humanDOA4 protein, S cerevisiae
Endosomal Sorting Complex Required for Transport LocationIn BloodProcess of secretionagonists

Papers overview

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2015
2015
Drosophila Vps4 promotes Epidermal growth factor receptor signaling independently of its role in receptor degradation
Endocytic trafficking of signaling receptors is an important mechanism for limiting signal duration. Components of the Endosomal… 
2015
2015
LUCID: A Quantitative Assay of ESCRT‐Mediated Cargo Sorting into Multivesicular Bodies
Endosomes are transportation nodes, mediating selective transport of soluble and transmembrane cargos to and from the Golgi… 
2014
2014
A genome-scale in vivo RNAi analysis of epithelial development in Drosophila identifies new proliferation domains outside of the stem cell niche
ABSTRACT The Drosophila oogenesis system provides an excellent model to study the development of epithelial tissues. Here, we… 
2014
2014
Expression of mutant CHMP2B, an ESCRT‐III component involved in frontotemporal dementia, causes eye deformities due to Notch misregulation in Drosophila
Endosomal sorting complexes required for transport (ESCRTs) mediate sorting of ubiquitinated membrane proteins into… 
2013
2013
A hydrophobic amino acid cluster inserted into the C-terminus of a recycling cell surface receptor functions as an endosomal sorting signal.
2013
2013
Relief of Autoinhibition Enhances Vta1 Activation of Vps4 via the Vps4 Stimulatory Element*
Background: Vta1 promotes Vps4 ATPase activity and facilitates ESCRT-III stimulation of Vps4. Results: The Vta1 VSE (Vps4… 
2012
2012
How HIV finds the door
The plasma membrane (PM) is a physical barrier that must be breached when pathogens like HIV enter and exit cells. In most cell… 
2011
2011
Genetic interactions with mutations affecting septin assembly reveal ESCRT functions in budding yeast cytokinesis
Abstract Membrane trafficking via targeted exocytosis to the Saccharomyces cerevisiae bud neck provides new membrane and membrane… 
2010
2010
The ESCRT machinery: a cellular apparatus for sorting and scission.
The ESCRT (endosomal sorting complex required for transport) machinery is a group of multisubunit protein complexes conserved… 
Review
2007
Review
2007
Structural studies of phosphoinositide 3-kinase-dependent traffic to multivesicular bodies.
Three large protein complexes known as ESCRT I, ESCRT II and ESCRT III drive the progression of ubiquitinated membrane cargo from… 
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