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Edeine

Known as: Edeine [Chemical/Ingredient] 
Basic peptide antibiotic from Bacillus brevis. It exhibits broad-spectrum antibacterial activity and inhibits bacterial DNA synthesis.
National Institutes of Health

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Highly Cited
2005
Highly Cited
2005
The hepatitis C virus (HCV) genome contains an internal ribosome entry site (IRES) followed by a large open reading frame coding… Expand
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Highly Cited
2004
Highly Cited
2004
The crystal structures of the universal translation-initiation inhibitors edeine and pactamycin bound to ribosomal 30S subunit… Expand
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Highly Cited
2001
Highly Cited
2001
The small ribosomal subunit is responsible for the decoding of genetic information and plays a key role in the initiation of… Expand
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Highly Cited
1991
Highly Cited
1991
We have studied the interactions of the antibiotics apramycin, kasugamycin, myomycin, neamine and pactamycin with 16S rRNA by… Expand
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Highly Cited
1987
Highly Cited
1987
Chemical footprinting shows that several classes of antibiotics (streptomycin, tetracycline, spectinomycin, edeine, hygromycin… Expand
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Highly Cited
1979
Highly Cited
1979
A number of translation inhibitors were tested for their effects on both control and encephalomyocarditis virus-infected mouse… Expand
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Highly Cited
1978
Highly Cited
1978
The antibiotic edenine induces binding of multiple 40 S ribosomes to reovirus messenger RNAs, producing complexes that sediment… Expand
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Highly Cited
1978
Highly Cited
1978
Three lines of evidence are presented indicating that GTP hydrolysis associated with eukaryotic peptide initiation occurs in the… Expand
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Highly Cited
1971
Highly Cited
1971
Edeine, a small basic peptide antibiotic, is shown to inhibit initiation of polyphenylalanine and globin peptides with little or… Expand
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Highly Cited
1967
Highly Cited
1967
Abstract Some 30 compounds have been selected which inhibit polypeptide synthesis from aminoacyl tRNA in 70-S ribosomal systems… Expand
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